February 16 – On orders from head of state Pasquale Paoli of the newly independent Republic of Corsica, a contingent of about 200 Corsican soldiers begins an invasion of the small island of Capraia off of the coast of northern Italy and territory of the Republic of Genoa. By May 31, the island is conquered as its defenders surrender.<ref name=Renwick>George Renwick, Romantic Corsica: Wanderings in Napoleon's Isle (Charles Scribner's Sons, 1910) p230</ref>
March 13 – British Chancellor of the ExchequerCharles Townshend, having already pushed through the unpopular Townshend Acts to recoup war expenses from Britain's American colonies, presents a comprehensive plan for more taxes in a closed door session of the House of Commons, with most proposals passed within a month.<ref>Ernest Rhys, ed., Memoirs of the Life and Writings of Benjamin Franklin (J.M. Dent & Sons, Ltd., 1916) p240</ref>
March 14 – Antonio de Ulloa, the Colonial Governor of Spanish Louisiana (Luisiana), dispatches Captain Francisco Ríu y Morales up the Mississippi River to establish two forts, one at San Luis (now St. Louis, Missouri) and to set up a colony for displaced French-speaking Acadians and protect shipping on the river.<ref>A. P. Nasatir, ed., Before Lewis and Clark: Documents Illustrating the History of the Missouri, 1785-1804 (University of Oklahoma Press, 1952) p65</ref>
March 24 – Spain acquires control of what are now called the Falkland Islands from France, compensating French Admiral Louis Antoine de Bougainville for the money spent on the construction of the settlement at Fort Saint Louis.<ref>G. Barnett Smith, The Romance of the South Pole: Antarctic Voyages and Explorations (Thomas Nelson and Sons, 1900) p16</ref> The islands, named les Îles Malouines by the French, are renamed las Islas Malvinas by the Spanish, and Fort Saint Louis is renamed as Puerto Soledad. In 1816, Argentina declares independence from Spain and takes the Malvinas; and in 1833, Britain's Royal Navy captures the islands from the Argentines and renames them the Falklands, and renames Puerto Soledad as Port Louis.
March 31 – Enforcement begins of the February 27 decree by King Carlos III of Spain, ordering the suppression of the Society of Jesus (the Jesuits) in the colonies in Spanish America. Over the next few months approximately 2,200 Jesuit priests and missionaries are deported.<ref>Enrique Dussel, A History of the Church in Latin America: Colonialism to Liberation (Wm. B. Eerdmans Publishing, 1981) p60</ref>
April 7 – Troops of the Burmese Konbaung dynasty sack the Siamese city of Ayutthaya, ending the Burmese–Siamese War (1765–67) after 15 months, and bringing the four-century-old Ayutthaya Kingdom to an end. King Ekkathat is found dead inside the city walls on April 9.<ref>"Legacy or Overhang: Historical Memory in Myanmar–Thai Relations", by Maung Aung Myoe, in Bilateral Legacies in East and Southeast Asia (Institute of Southeast Asian Studies, 2015) p113</ref>
May 3 – A fleet of ships from the Republic of Genoa arrives at Capraia and sends 150 men ashore to drive out the Corsicans, but the outnumbered Genoese marines are "quickly cut to pieces".<ref name=Renwick/>
May 10 – Sir William Johnson, 1st Baronet, acting on behalf of Great Britain, meets with representatives of the Six Nations of the Iroquois Confederacy at German Flatts, New York, opening negotiations on the boundary between the New York colony and the Native Americans, eventually concluded by the Treaty of Fort Stanwix.<ref>The Papers of Sir William Johnson, ed. by James Sullivan (University of the State of New York, 1921) p xxx</ref>
May 16 – Ahmed al-Ghazzal, the emissary from Sultan Mohammed ben Abdallah of Morocco to the Spanish Empire, makes a triumphant return to Marrakesh with almost 300 Muslims who had been held captive in Spain, as well as sacred Islamic manuscripts that had been seized by the Spanish in 1612. The negotiation of the release had started with al-Ghazzal's meeting with Spain's King Carlos III on August 21, 1766.<ref>Abdulrahman al-Ruwaishan translator and Travis Landry, editor, The Fruits of the Struggle in Diplomacy and War: Moroccan Ambassador al-Ghazzal and His Diplomatic Retinue in Eighteenth-Century Andalusia (Bucknell University Press, 2016) pp9-10</ref>
May 31 – The Genoese island of Capraia is conquered by the Corsican Army after a ten-week campaign.<ref name=Renwick/>
Pitcairn Island in the Pacific Ocean is sighted from HMS Swallow, by 15-year-old MidshipmanRobert Pitcairn, on a British Royal Navy expeditionary voyage commanded by Philip Carteret, the first definite European sighting.
Norway's oldest newspaper still in print, Adresseavisen, is first published.
August 26 – Construction begins on Tryon Palace in New Bern, North Carolina. The construction proves more expensive than initially expected, leading the government to increase local taxes. This stirs resentment among some North Carolinians, and helps prolong the War of the Regulation.
September 29 – The Spanish Empire's Governorate of the Río de la Plata and Governorate of Paraguay begin the process of expulsion of the 456 members of the Society of Jesus (the Jesuits) from southern South America, placing them on five ships bound for Spain.<ref>Miguel de Asúa, Science in the Vanished Arcadia: Knowledge of Nature in the Jesuit Missions of Paraguay and Río de la Plata (BRILL, 2014) p259</ref>
October 9 – Surveying of the "Mason–Dixon line", which will later become the traditional division between the northern and southern states of the United States, is completed by Charles Mason and Jeremiah Dixon after four years, initially to settle a boundary dispute between the colonies of Delaware, Pennsylvania and Maryland. The survey party is halted at Dunkard Creek when a chief of the Mohawk Indians tells them that they are in Native American territory and that the Mohawks guiding the property "would not proceed one step further Westward"; the line, slightly west the 80th meridian west, is now part of the boundary between Pennsylvania and West Virginia.<ref>Sally M. Walker, Boundaries: How the Mason-Dixon Line Settled a Family Feud and Divided a Nation (Candlewick Press, 2014) pp146-147</ref>
October 12 – At the Foundling Hospital in London, Dr. William Watson becomes the first physician to conduct a controlled clinical trial, selecting 32 boys and girls of similar age who have not yet had smallpox. He divides them into three groups in order to test treatments before inoculation for smallpox, with one group receiving a mixture of mercury and jalap, another senna glycoside, and the third getting no pre-treatment at all.<ref>Shein-Chung Chow and Jen-Pei Liu, Design and Analysis of Clinical Trials: Concepts and Methodologies (John Wiley & Sons, 2008) p108</ref>
October 17 – Šćepan Mali, nicknamed "Stephen the Little", is selected as the legislature at Podgorica to be the Tsar of Montenegro, representing "a short but an important break in the succession of the Petrovic dynasty".<ref>Marija Krivokapić and Neil Diamond, Images of Montenegro in Anglo-American Creative Writing and Film (Cambridge Scholars Publishing, 2017) p10</ref>
October 24 – In France, several anti-Jewish regulations in place since October 12, 1661, are repealed by the King's Council that advises Louis XV of France. While Jewish merchants are still prohibited from owning their own retail stores, they are allowed to sell merchandise on credit to gentile merchants at legal interest rates, to legally enforce debts, and to sell jewelry.<ref>Zosa Szajkowski, Jews and the French Revolutions of 1789, 1830 and 1848 (Ktav Publishing House, 1970) p302</ref>
October 28 – A boycott, of 38 types of goods <ref>Edmund S. Morgan, Benjamin Franklin (Yale University Press, 2002) p167</ref> imported from England, is resolved by Boston merchants meeting at Faneuil Hall as a response to the taxes imposed by Great Britain, and one of the first "Buy American" campaigns is started in order to encourage the purchase of items manufactured and produced in the 13 colonies.<ref>Ann Fairfax Withington, Toward a More Perfect Union: Virtue and the Formation of American Republics (Oxford University Press, 1996) p99</ref> Copies of the agreement, to be signed by participating merchants, are circulated beyond the Province of Massachusetts Bay to other colonial provinces in New England.<ref>John C. Redmond, Three To Ride: A Ride That Defied An Empire and Spawned A New Nation (Hamilton Books, 2012) p137</ref>
November 1 – Scottish-born American merchant and shipowner Andrew Sprowle of Portsmouth, Virginia, establishes the Gosport Shipyard on the western shore of the Elizabeth River in the Virginia Colony, on the site of what will eventually become the Norfolk Naval Shipyard.<ref>"Gosport Navy Yard", in The Encyclopedia of the Wars of the Early American Republic, 1783–1812: A Political, Social, and Military History, by Spencer C. Tucker (ABC-CLIO, 2014) p274</ref>
November 3 – King Ferdinand IV of the Spanish dominated Kingdom of Naples follows Spain's lead and orders the expulsion of the Jesuits from Naples and has them marched northward to the Neapolitan border with the Papal States.<ref>Norma Bouchard and Valerio Ferme, Italy and the Mediterranean: Words, Sounds, and Images of the Post-Cold War Era (Palgrave Macmillan, 2013) p49</ref>
November 4 – Francisco de Paula Bucareli, the Governor of Buenos Aires (at the time, a province within the Spanish Empire's Viceroyalty of Peru), hosts the caciques who are the Guarani chiefs of the 30 mission towns established by Jesuit missionaries, in an effort to gain Guarani peoples' support in the expulsion of the Jesuits.<ref>Barbara Ganson, The Guarani Under Spanish Rule in the Rio de la Plata (Stanford University Press, 2005) p121</ref>
November 9 – At the new King's College medical school in New York City (later the Columbia University College of Physicians and Surgeons), Dr. John Jones gives the first lecture by a surgical professor in North America.<ref>A Reference Handbook of the Medical Sciences, Volume VIII, ed. by Thomas Lathrop Stedmon (William Wood and Co., 1917) p46</ref>
November 14 – The Timucua Indian tribe, native to central Florida, becomes extinct with the death of the last speaker of the Timucuan language, Juan Alonso Cabale. Eight years earlier, the last 95 surviving Timucuan people had been forcibly relocated by the Spanish colonial government to Guanabacoa, a township in western Cuba.<ref>Maurice J. Robinson, Ponte Vedra Beach: A History (Arcadia Publishing, 2008)</ref>
November 19 – Under the coercion of Russian occupation armies, the legislature of Poland follows the wishes of Russian Minister Nicholas Repnin and agrees to allow the kingdom to become a Russian protectorate.<ref>Albert Sorel, The Eastern Question in the Eighteenth Century (Methuen & Company, 1898) pp22-23</ref>
November 20 – The new American Colonies Act 1766, commonly called the "Declaratory Act", goes into effect, virtually providing for Great Britain's Parliament to govern lawmaking in 13 colonies and exacerbating tensions there.<ref>Edward G. Lengel, First Entrepreneur: How George Washington Built His--and the Nation's--Prosperity (Da Capo Press, 2016) p76</ref>
November 27 – Oconostota and Attakullakulla, Chiefs of the Cherokee people in the Carolinas, depart from Charleston, South Carolina on a ship voyage to New York City, where they are welcomed by British colonial officials as a prelude to negotiations with Britain's Superintendent of Indian Affairs, Sir William Johnson.<ref name=Weaver>Jace Weaver, The Red Atlantic: American Indigenes and the Making of the Modern World, 1000-1927 (University of North Carolina Press Books, 2014) p164</ref>
November 29 – The Archduchess Maria Theresa of Austria, in her capacity as Queen of Hungary, issues an edict against the Romani people (commonly called the gypsies), prohibiting them from marrying and calling for gypsy children to be taken away by the government so that they can be brought up by Christian families, a proclamation that "produced little or no effect in comparison with the trouble involved".<ref>The World's History: A Survey of Man's Record, Volume V: South-Eastern and Eastern Europe edited by H. F. Helmolt (William Heinemann, 1907) p423</ref>
December 28 – PhrayaTaksin, a minor provincial official in Siam (now Thailand), crowns himself as King of Siam, establishing the Siamese Thonburi Kingdom, taking the regnal name of Borommaracha IV and begins a 14-year reign of liberation and conquest; historically, he is known as "Taksin the Great".<ref>Antonio L. Rappa, The King and the Making of Modern Thailand (Taylor & Francis, 2017) p224</ref>
December 29 – Oconostota and Attakullakulla arrive at Johnstown, New York where they, along with leaders of the Six Nations of the Iroquois Confederacy (the Mohawk, Onondaga, Oneida, Cayuga, Seneca and Tuscarora tribal nations) meet with Sir William Johnson to begin peace negotiations with the British Empire.<ref name=Weaver/>