Editing Gonad (section)

===Testicular aging===
The testes of older men often have [[sperm]] abnormalities that can ultimately lead to [[male infertility]].<ref name = Dong2022/>  These abnormalities include accumulation of DNA damage and decreased DNA repair ability.<ref name = Dong2022>{{cite journal |vauthors=Dong S, Chen C, Zhang J, Gao Y, Zeng X, Zhang X |title=Testicular aging, male fertility and beyond |journal=Front Endocrinol (Lausanne) |volume=13 |issue= |pages=1012119 |date=2022 |pmid=36313743 |pmc=9606211 |doi=10.3389/fendo.2022.1012119 |doi-access=free}}</ref>  During spermatogenesis in the testis, spontaneous new mutations arise and tend to accumulate with age.<ref>{{cite book |vauthors=Cioppi F, Casamonti E, Krausz C |title=Genetic Damage in Human Spermatozoa |chapter=Age-Dependent De Novo Mutations During Spermatogenesis and Their Consequences |series=Adv Exp Med Biol |volume=1166 |pages=29–46 |date=2019 |pmid=31301044 |doi=10.1007/978-3-030-21664-1_2 |isbn=978-3-030-21663-4 }}</ref>