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Vesicle (biology and chemistry)
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===Protocells=== The [[RNA world]] hypothesis assumes that the first [[self-replication|self-replicating]] [[genome]]s were strands of RNA. This hypothesis contains the idea that RNA strands formed [[ribozymes]] (folded RNA molecules) capable of catalyzing RNA replication. These primordial biological catalysis were considered to be contained within vesicles ([[protocell]]s) with membranes composed of [[fatty acid]]s and related [[amphiphile]]s.<ref name="Adamala2013">{{cite journal |vauthors=Adamala K, Szostak JW |title=Nonenzymatic template-directed RNA synthesis inside model protocells |journal=Science |volume=342 |issue=6162 |pages=1098β1100 |date=November 2013 |pmid=24288333 |pmc=4104020 |doi=10.1126/science.1241888 |bibcode=2013Sci...342.1098A }}</ref> Template-directed RNA synthesis by the copying of RNA templates inside fatty acid vesicles has been demonstrated by Adamata and Szostak.<ref name = Adamala2013/>
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