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== Vaccine == There is a polyvalent inactivated vaccine against several types of ''Streptococcus'' including ''S. pyogenes'' called "vacuna antipiogena polivalente BIOL". It is recommended to be administered in a 5 week series. Two weekly applications are made at intervals of 2 to 4 days. The vaccine is produced by the Instituto Biológico Argentino.<ref>{{cite web|url=https://biol.com.ar/uploads/filemanager/Vacuna%20Antipiogena%20Biol.pdf |archive-url=https://ghostarchive.org/archive/20221010/https://biol.com.ar/uploads/filemanager/Vacuna%20Antipiogena%20Biol.pdf |archive-date=October 10, 2022 |url-status=live|title=Package leaflet on BIOL official website}}</ref> There is another potential vaccine being developed; the vaccine candidate peptide is called StreptInCor.<ref>{{cite journal | vauthors = Guilherme L, Ferreira FM, Köhler KF, Postol E, Kalil J | title = A vaccine against Streptococcus pyogenes: the potential to prevent rheumatic fever and rheumatic heart disease | journal = American Journal of Cardiovascular Drugs | volume = 13 | issue = 1 | pages = 1–4 | date = February 2013 | pmid = 23355360 | doi = 10.1007/s40256-013-0005-8 | s2cid = 13071864 | doi-access = free }}</ref>
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