Editing Morphogenesis (section)

==Virus morphogenesis==

During assembly of the [[Escherichia virus T4|bacteriophage (phage) T4]] [[virus|virion]], the morphogenetic proteins encoded by the phage [[gene]]s interact with each other in a characteristic sequence.  Maintaining an appropriate balance in the amounts of each of these proteins produced during viral infection appears to be critical for normal phage T4 morphogenesis.<ref>{{cite journal | doi=10.1016/0022-2836(70)90303-7 | title=Interaction of morphogenetic genes of bacteriophage T4 | year=1970 | last1=Floor | first1=Erik | journal=Journal of Molecular Biology | volume=47 | issue=3 | pages=293–306 | pmid=4907266 }}</ref>  Phage T4 encoded proteins that determine virion structure include major structural components, minor structural components and non-structural proteins that catalyze specific steps in the morphogenesis sequence.<ref>{{cite journal | doi=10.1016/0042-6822(68)90285-7 | title=Dominance interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product function: Catalytic vs. Stoichiometric | year=1968 | last1=Snustad | first1=D.Peter | journal=Virology | volume=35 | issue=4 | pages=550–563 | pmid=4878023 }}</ref>  Phage T4 morphogenesis is divided into three independent pathways: the head, the tail and the long tail fibres as detailed by Yap and Rossman.<ref>{{cite journal | doi=10.2217/fmb.14.91 | title=Structure and function of bacteriophage T4 | year=2014 | last1=Yap | first1=Moh Lan | last2=Rossmann | first2=Michael G. | journal=Future Microbiology | volume=9 | issue=12 | pages=1319–1327 | pmid=25517898 | pmc=4275845 }}</ref>