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==MMRV vaccine== {{main|MMRV vaccine}} The [[MMRV vaccine]], a combined measles, mumps, rubella, and [[varicella]] (chickenpox) vaccine, has been proposed as a replacement for the MMR vaccine to simplify the administration of the vaccines.<ref name=Vesikari>{{cite journal | vauthors = Vesikari T, Sadzot-Delvaux C, Rentier B, Gershon A | title = Increasing coverage and efficiency of measles, mumps, and rubella vaccine and introducing universal varicella vaccination in Europe: a role for the combined vaccine | journal = The Pediatric Infectious Disease Journal | volume = 26 | issue = 7 | pages = 632β638 | date = July 2007 | pmid = 17596807 | doi = 10.1097/INF.0b013e3180616c8f | s2cid = 41981427 }}</ref> Preliminary data indicate a rate of [[febrile seizures]] of 9 per 10,000 vaccinations with MMRV, as opposed to 4 per 10,000 for separate MMR and varicella shots; US health officials therefore, do not express a preference for use of MMRV vaccine over separate injections.<ref name=klein08>{{cite journal | title = Update: recommendations from the Advisory Committee on Immunization Practices (ACIP) regarding administration of combination MMRV vaccine | journal = MMWR. Morbidity and Mortality Weekly Report | volume = 57 | issue = 10 | pages = 258β260 | date = March 2008 | pmid = 18340332 | url = <!-- Official URL --> https://www.cdc.gov/mmwr/PDF/wk/mm5710.pdf | access-date = 26 January 2020 | url-status = live | archive-url = https://web.archive.org/web/20201019154628/https://www.cdc.gov/mmwr/PDF/wk/mm5710.pdf | archive-date = 19 October 2020 | author1 = Centers for Disease Control and Prevention (CDC) | author2 = Advisory Committee on Immunization Practices (ACIP) }}</ref> In a 2012 study<ref>{{cite journal | vauthors = O'Leary ST, Suh CA, Marin M | title = Febrile seizures and measles-mumps-rubella-varicella (MMRV) vaccine: what do primary care physicians think? | journal = Vaccine | volume = 30 | issue = 48 | pages = 6731β6733 | date = November 2012 | pmid = 22975026 | doi = 10.1016/j.vaccine.2012.08.075 }}</ref> pediatricians and family doctors were sent a survey to gauge their awareness of the increased risk of febrile seizures (fever fits) in the MMRV. 74% of family doctors and 29% of pediatricians were unaware of the increased risk of febrile seizures. After reading an informational statement only 7% of family doctors and 20% of pediatricians would recommend the MMRV for a healthy 12- to 15-month-old child. The factor that was reported as the "most important" deciding factor in recommending the MMRV over the MMR+V was [[Advisory Committee on Immunization Practices|ACIP]]/[[AAFP]]/[[American Academy of Pediatrics|AAP]] recommendations (pediatricians, 77%; family physicians, 73%).
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