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===Classification by type of ions=== * [[Chloride channel]]s: This superfamily of channels consists of approximately 13 members. They include ClCs, CLICs, Bestrophins and CFTRs. These channels are non-selective for small anions; however [[chloride]] is the most abundant anion, and hence they are known as chloride channels. * [[Potassium channel]]s ** [[Voltage-gated potassium channel]]s e.g., Kvs, Kirs etc. ** [[Calcium-activated potassium channel]]s e.g., BKCa or MaxiK, SK, etc. ** [[Inward-rectifier potassium ion channel|Inward-rectifier potassium channels]] ** [[Two P potassium channel|Two-pore-domain potassium channels]]: This family of 15 members form what is known as [[leak channel]]s, and they display [[GHK current equation|Goldman-Hodgkin-Katz]] (open) [[rectifier|rectification]]. * [[Sodium channels]] ** [[Voltage-gated sodium channel]]s (NaVs) ** [[Epithelial sodium channel]]s (ENaCs)<ref name="2016-Hanukoglu" >{{cite journal | vauthors = Hanukoglu I, Hanukoglu A | title = Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases | journal = Gene | volume = 579 | issue = 2 | pages = 95β132 | date = April 2016 | pmid = 26772908 | pmc = 4756657 | doi = 10.1016/j.gene.2015.12.061 }}</ref> * [[Calcium channel]]s (CaVs) * Phosphate channels: To date, only one phosphate channel, [[Xenotropic and polytropic retrovirus receptor 1]] (XPR1), has been identified in animals. It is a pyrophosphate-gated channel.<ref>{{Cite journal |last1=Lu |first1=Yi |last2=Yue |first2=Chen-Xi |last3=Zhang |first3=Li |last4=Yao |first4=Deqiang |last5=Xia |first5=Ying |last6=Zhang |first6=Qing |last7=Zhang |first7=Xinchen |last8=Li |first8=Shaobai |last9=Shen |first9=Yafeng |last10=Cao |first10=Mi |last11=Guo |first11=Chang-Run |last12=Qin |first12=An |last13=Zhao |first13=Jie |last14=Zhou |first14=Lu |last15=Yu |first15=Ye |date=2024-09-26 |title=Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1 |url=https://www.science.org/doi/10.1126/science.adp3252 |journal=Science |volume=386 |issue=6723 |pages=eadp3252 |language=en |doi=10.1126/science.adp3252 |pmid=39325866 |bibcode=2024Sci...386P3252L |issn=0036-8075}}</ref> * Proton channels ** [[Voltage-gated proton channels]] * ''Non-selective cation channels'': These non-selectively allow many types of cations, mainly Na<sup>+</sup>, K<sup>+</sup> and Ca<sup>2+</sup>, through the channel. ** Most [[transient receptor potential|transient receptor potential channels]]
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