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===Symptomatic diagnostics=== The diagnosis is aided by the presenting symptoms in any individual with an infectious disease, yet it usually needs additional diagnostic techniques to confirm the suspicion. Some signs are specifically characteristic and indicative of a disease and are called [[pathognomonic]] signs; but these are rare. Not all infections are symptomatic.<ref name=Sternak>{{cite journal|last1=Ljubin-Sternak|first1=Suncanica|last2=Mestrovic|first2=Tomislav|title=Review: Chlamydia trachonmatis and Genital Mycoplasmias: Pathogens with an Impact on Human Reproductive Health|journal=Journal of Pathogens|page=3 |date=2014|volume=2014|issue=183167|doi=10.1155/2014/183167|pmid=25614838|pmc=4295611|doi-access=free}}</ref> In children the presence of [[cyanosis]], rapid breathing, poor peripheral perfusion, or a [[petechial rash]] increases the risk of a serious infection by greater than 5 fold.<ref name=Lancet10>{{cite journal |vauthors=Van den Bruel A, Haj-Hassan T, Thompson M, Buntinx F, Mant D | title = Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review | journal = Lancet | volume = 375 | issue = 9717 | pages = 834β45 | date = March 2010 | pmid = 20132979 | doi = 10.1016/S0140-6736(09)62000-6 | s2cid = 28014329 }}</ref> Other important indicators include parental concern, clinical instinct, and temperature greater than 40 Β°C.<ref name=Lancet10/>
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