Editing Glutathione (section)

===In plants===
In plants, glutathione is involved in stress management. It is a component of the [[glutathione-ascorbate cycle]], a system that reduces poisonous [[hydrogen peroxide]].<ref name=Noctor >{{cite journal | vauthors = Noctor G, Foyer CH | title = Ascorbate and Glutathione: Keeping Active Oxygen Under Control | journal = Annual Review of Plant Physiology and Plant Molecular Biology | volume = 49 | issue = 1 | pages = 249–279 | date = June 1998 | pmid = 15012235 | doi = 10.1146/annurev.arplant.49.1.249 }}</ref> It is the precursor of [[phytochelatins]], glutathione [[oligomer]]s that [[chelate]] heavy metals such as [[cadmium]].<ref>{{cite journal | vauthors = Ha SB, Smith AP, Howden R, Dietrich WM, Bugg S, O'Connell MJ, Goldsbrough PB, Cobbett CS | title = Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe | journal = The Plant Cell | volume = 11 | issue = 6 | pages = 1153–64 | date = June 1999 | pmid = 10368185 | pmc = 144235 | doi = 10.1105/tpc.11.6.1153 }}</ref> Glutathione is required for efficient defence against plant pathogens such as ''[[Pseudomonas syringae]]'' and ''[[Phytophthora]] brassicae''.<ref name=Parisy >{{cite journal | vauthors = Parisy V, Poinssot B, Owsianowski L, Buchala A, Glazebrook J, Mauch F | title = Identification of PAD2 as a gamma-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis | journal = The Plant Journal | volume = 49 | issue = 1 | pages = 159–172 | date = January 2007 | pmid = 17144898 | doi = 10.1111/j.1365-313X.2006.02938.x | url = http://doc.rero.ch/record/6306/files/mauch_ipg.pdf | doi-access = free }}</ref> [[Adenylyl-sulfate reductase]], an enzyme of the [[sulfur assimilation]] pathway, uses glutathione as an electron donor. Other enzymes using glutathione as a substrate are [[glutaredoxin]]s. These small [[oxidoreductases]] are involved in flower development, [[salicylic acid]], and plant defence signalling.<ref name=Rouhier >{{cite journal | vauthors = Rouhier N, Lemaire SD, Jacquot JP | title = The role of glutathione in photosynthetic organisms: emerging functions for glutaredoxins and glutathionylation | journal = Annual Review of Plant Biology | volume = 59 | issue = 1 | pages = 143–166 | year = 2008 | pmid = 18444899 | doi = 10.1146/annurev.arplant.59.032607.092811 | bibcode = 2008AnRPB..59..143R | url = https://hal.inrae.fr/hal-02660326/file/2008%20Rouhier%20Jacquot%20ARPB.pdf }}</ref>