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== Chromosomal disorder == {{See also|Chromosome abnormality}} [[File:Down_Syndrome_Karyotype.png|thumb|Chromosomes in [[Down syndrome]], the most common human condition due to aneuploidy. There are three chromosomes 21 (in the last row).]] A chromosomal disorder is a missing, extra, or irregular portion of chromosomal DNA.<ref>{{Cite web |title=Genetic Disorders: What Are They, Types, Symptoms & Causes |url=https://my.clevelandclinic.org/health/diseases/21751-genetic-disorders |access-date=2023-11-01 |website=Cleveland Clinic |language=en |archive-date=2023-11-01 |archive-url=https://web.archive.org/web/20231101015655/https://my.clevelandclinic.org/health/diseases/21751-genetic-disorders |url-status=live }}</ref> It can be from an atypical number of chromosomes or a structural abnormality in one or more chromosomes. An example of these disorders is Trisomy 21 (the most common form of [[Down syndrome]]), in which there is an extra copy of chromosome 21 in all cells.<ref>{{Cite web |last=CDC |date=2023-10-10 |title=Facts about Down Syndrome {{!}} CDC |url=https://www.cdc.gov/ncbddd/birthdefects/downsyndrome.html |access-date=2023-11-01 |website=Centers for Disease Control and Prevention |language=en-us |archive-date=2017-07-28 |archive-url=https://web.archive.org/web/20170728031507/https://www.cdc.gov/ncbddd/birthdefects/DownSyndrome.html |url-status=live }}</ref>
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