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==== Public Perceptions ==== Some who advocate against food irradiation argue the long-term health effects and safety of irradiated food cannot be scientifically proven, however there have been hundreds of animal feeding studies of irradiated food performed since 1950.<ref name="JFDiehl">Diehl, J.F., Safety of irradiated foods, Marcel Dekker, N.Y., 1995 (2. ed.)</ref> Endpoints include subchronic and chronic changes in [[metabolism]], [[histopathology]], function of most [[organ (anatomy)|organs]], reproductive effects, growth, [[teratogenicity]], and [[mutagenicity]].<ref name="JFDiehl"/><ref name="JECFI">World Health Organization. Wholesomeness of irradiated food. Geneva, Technical Report Series No. 659, 1981</ref><ref name="JSGHDI">World Health Organization. High-Dose Irradiation: Wholesomeness of Food Irradiated With Doses Above 10 kGy. Report of a Joint FAO/IAEA/WHO Study Group. Geneva, Switzerland: World Health Organization; 1999. WHO Technical Report Series No. 890</ref><ref name="FDA1986">US Department of Health, and Human Services, Food, and Drug Administration Irradiation in the production, processing, and handling of food. Federal Register 1986; 51:13376-13399</ref>
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