Editing Flunitrazepam (section)

==Overdose==
{{See also|Benzodiazepine overdose}}
Flunitrazepam is a drug that is frequently involved in drug intoxication, including overdose.<ref>{{cite journal | vauthors = Zevzikovas A, Kiliuviene G, Ivanauskas L, Dirse V | title = [Analysis of benzodiazepine derivative mixture by gas-liquid chromatography] | journal = Medicina | volume = 38 | issue = 3 | pages = 316–320 | year = 2002 | pmid = 12474705 }}</ref><ref>{{cite journal | vauthors = Jonasson B, Saldeen T | title = Citalopram in fatal poisoning cases | journal = Forensic Science International | volume = 126 | issue = 1 | pages = 1–6 | date = March 2002 | pmid = 11955823 | doi = 10.1016/S0379-0738(01)00632-6 }}</ref> Overdose of flunitrazepam may result in excessive sedation, or impairment of balance or speech. This may progress in severe overdoses to [[respiratory depression]] or coma and possibly death. The risk of overdose is increased if flunitrazepam is taken in combination with [[Cns depressants|CNS depressants]] such as [[ethanol]] (alcohol) and [[opioid]]s. Flunitrazepam overdose responds to the [[GABAA receptor|GABA<sub>A</sub> receptor]] antagonist [[flumazenil]], which thus can be used as a treatment.