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=== As an antioxidative enzyme === [[File:Removal of O2- and H2O2 by cytochrome c.png|thumb|Removal of {{chem2|O2-}} and H{{sub|2}}O{{sub|2}} by cytochrome c]] In addition to its well-known roles in the electron transport chain and cell apoptosis, according to a 2008 study cytochrome c can also act as an antioxidative enzyme in the mitochondria; it does so by removing [[superoxide]] ({{chem2|O2-}}) and [[hydrogen peroxide]] (H{{sub|2}}O{{sub|2}}) from [[mitochondria]].<ref name="Bowman_2008">{{Cite journal |vauthors=Bowman SE, Bren KL |date=December 2008 |title=The chemistry and biochemistry of heme c: functional bases for covalent attachment |journal=Natural Product Reports |volume=25 |issue=6 |pages=1118β30 |doi=10.1039/b717196j |pmc=2654777 |pmid=19030605}}</ref> Therefore, not only is cytochrome c required in the mitochondria for cellular respiration, but it is also needed in the mitochondria to limit the production of {{chem2|O2-}} and {{chem2|H2O2}}.<ref name="Bowman_2008" />
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