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==Regulation and composition== CoQ<sub>10</sub> is not approved by the U.S. [[Food and Drug Administration]] (FDA) for the treatment of any medical condition.<ref name="canter-patient">{{Include-USGov|agency=[[National Cancer Institute]]|url=http://www.cancer.gov/cancertopics/pdq/cam/coenzymeQ10/patient|publisher=[[National Cancer Institute]]|title=Coenzyme Q<sub>10</sub>|date=April 2022}}</ref><ref name="pmid26389329">{{cite book|pmid=26389329 |date=2002 |publisher=PDQ Integrative, Alternative, and Complementary Therapies Editorial Board |title=Coenzyme Q10: Health Professional Version |author=((PDQ Integrative, Alternative, and Complementary Therapies Editorial Board)) }}</ref><ref name="White-2014">{{Include-USGov|agency=[[National Cancer Institute]]| vauthors = White J |date= 14 May 2014 |title=PDQ Coenzyme Q<sub>10</sub> |url=http://www.cancer.gov/cancertopics/pdq/cam/coenzymeQ10/HealthProfessional |publisher= [[National Cancer Institute]], [[National Institutes of Health]], [[United States Department of Health and Human Services|U.S. Dept. of Health and Human Services]] |access-date= 29 June 2014}}</ref><ref name="nice.org.uk-2017">{{Cite web |url=https://www.nice.org.uk/advice/es11/resources/mitochondrial-disorders-in-children-coenzyme-q10-pdf-1158110303173 |title=Mitochondrial disorders in children: Co-enzyme Q10 |date=28 March 2017 |website=nice.org.uk |publisher=National Institute for Health and Care Excellence |location=UK |access-date=10 October 2019 |archive-date=10 October 2019 |archive-url=https://web.archive.org/web/20191010120754/https://www.nice.org.uk/advice/es11/resources/mitochondrial-disorders-in-children-coenzyme-q10-pdf-1158110303173 |url-status=live }}</ref> However, it is sold as a [[dietary supplement]] not subject to the same [[Regulation of therapeutic goods|regulations as medicinal drugs]], and is an ingredient in some cosmetics.<ref name="pmid10953455">{{cite journal | vauthors = Hojerová J | title = [Coenzyme Q10--its importance, properties and use in nutrition and cosmetics] | journal = Ceska a Slovenska Farmacie | volume = 49 | issue = 3 | pages = 119–123 | date = May 2000 | pmid = 10953455 }}</ref> The manufacture of CoQ<sub>10</sub> is not regulated, and different batches and brands may vary significantly.<ref name="White-2014"/>
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