Editing Circadian rhythm (section)

== Other synchronizers of circadian rhythms ==
Although light is the primary synchronizer of the circadian rhythm through the suprachiasmatic nucleus (SCN), other environmental signals also influence the biological clock. Feeding plays a key role in regulating peripheral clocks found in the liver, muscles, and adipose tissues. Time-restricted feeding can adjust these clocks by modifying light signals. Additionally, physical activity affects the circadian phase, notably by adjusting melatonin production and body temperature. Temperature itself is an important synchronizer, capable of modifying cellular circadian rhythms. Finally, stress and the release of glucocorticoids influence the expression of clock genes, potentially disrupting biological cycles. Integrating these factors is essential for understanding circadian rhythms beyond simple light regulation.<ref>{{Cite journal |last1=Takahashi |first1=Joseph S. |year=2017 |title=Transcriptional architecture of the mammalian circadian clock |journal=Nature Reviews Genetics |volume=18 |issue=3 |pages=164–179 |doi=10.1038/nrg.2016.150 |pmc=5501165 |pmid=27990019}}</ref>