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===Regulation=== The composition and rate of CSF generation are influenced by hormones and the content and pressure of blood and CSF.<ref name="SAKKA2011"/> For example, when CSF pressure is higher, there is less of a pressure difference between the capillary blood in choroid plexuses and CSF, decreasing the rate at which fluids move into the choroid plexus and CSF generation.<ref name="SAKKA2011"/> The [[autonomic nervous system]] influences choroid plexus CSF secretion, with activation of the [[sympathetic nervous system]] decreasing secretion and the [[parasympathetic nervous system]] increasing it.<ref name="SAKKA2011"/> Changes in the [[pH#pH of various body fluids|pH of the blood]] can affect the activity of [[carbonic anhydrase]], and some drugs (such as [[furosemide]], acting on the [[Na-K-Cl cotransporter]]) have the potential to impact membrane channels.<ref name="SAKKA2011"/>
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