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===Medical and dental uses=== Casein-derived compounds are used in [[Remineralisation of teeth|tooth remineralization]] products to stabilize [[amorphous calcium phosphate]] (ACP) and release the ACP onto tooth surfaces, where it can facilitate remineralization.<ref>{{Cite journal| vauthors = Malcmacher L |journal=Dentistry Today|title=Enamel Remineralization: The Medical Model of Practicing multi Dentistry|date=8 February 2011|url=http://www.dentistrytoday.com/hygiene/1164}}</ref><ref>{{cite journal | vauthors = Walker G, Cai F, Shen P, Reynolds C, Ward B, Fone C, Honda S, Koganei M, Oda M, Reynolds E | display-authors = 6 | title = Increased remineralization of tooth enamel by milk containing added casein phosphopeptide-amorphous calcium phosphate | journal = The Journal of Dairy Research | volume = 73 | issue = 1 | pages = 74β78 | date = February 2006 | pmid = 16433964 | doi = 10.1017/S0022029905001482 | s2cid = 43342264 }}</ref><ref name="Chhabra Chhabra pp. 1β10">{{cite journal|vauthors=Chhabra N, Chhabra A|date=2018|title=Enhanced Remineralisation of Tooth Enamel Using Casein Phosphopeptide-Amorphous Calcium Phosphate Complex: A Review|journal=International Journal of Clinical Preventive Dentistry|volume=14|issue=1|pages=1β10|doi=10.15236/ijcpd.2018.14.1.1}}</ref> Casein and [[gluten]] [[exclusion diet]]s are sometimes used in [[alternative medicine]] for children with [[autism]]. As of 2015 the evidence that such diets have any impact on behavior or cognitive and social functioning in autistic children was limited and weak.<ref>{{cite journal | vauthors = Lange KW, Hauser J, Reissmann A | title = Gluten-free and casein-free diets in the therapy of autism | journal = Current Opinion in Clinical Nutrition and Metabolic Care | volume = 18 | issue = 6 | pages = 572β575 | date = November 2015 | pmid = 26418822 | doi = 10.1097/mco.0000000000000228 | s2cid = 271720 }}</ref><ref name="Cochrane2008">{{cite journal | vauthors = Millward C, Ferriter M, Calver S, Connell-Jones G | title = Gluten- and casein-free diets for autistic spectrum disorder | journal = The Cochrane Database of Systematic Reviews | issue = 2 | pages = CD003498 | date = April 2008 | pmid = 18425890 | pmc = 4164915 | doi = 10.1002/14651858.CD003498.pub3 | type = Systematic Review }}</ref>
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