Editing Asthma (section)

===Medical conditions===
A triad of [[atopic eczema]], [[allergic rhinitis]] and asthma is called atopy.<ref name="Bolognia" /> The strongest risk factor for developing asthma is a history of [[atopy|atopic disease]];<ref name=NHLBI07p11/> with asthma occurring at a much greater rate in those who have either [[eczema]] or [[Rhinitis|hay fever]].<ref name="GINA2011_p4">{{harvnb|GINA|2011|p=4}}</ref> Asthma has been associated with [[eosinophilic granulomatosis with polyangiitis]] (formerly known as Churg–Strauss syndrome), an autoimmune disease and [[vasculitis]].<ref name="ChapelHill">{{cite journal | vauthors = Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, Flores-Suarez LF, Gross WL, Guillevin L, Hagen EC, Hoffman GS, Jayne DR, Kallenberg CG, Lamprecht P, Langford CA, Luqmani RA, Mahr AD, Matteson EL, Merkel PA, Ozen S, Pusey CD, Rasmussen N, Rees AJ, Scott DG, Specks U, Stone JH, Takahashi K, Watts RA | display-authors = 6 | title = 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides | journal = Arthritis and Rheumatism | volume = 65 | issue = 1 | pages = 1–11 | date = January 2013 | pmid = 23045170 | doi = 10.1002/art.37715 | doi-access = free }}</ref> Individuals with certain types of [[urticaria]] may also experience symptoms of asthma.<ref name="Bolognia">{{cite book | vauthors = Rapini RP, Bolognia JL, Jorizzo JL |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1 }}</ref>

There is a correlation between [[obesity]] and the risk of asthma with both having increased in recent years.<ref>{{cite journal | vauthors = Beuther DA | title = Recent insight into obesity and asthma | journal = Current Opinion in Pulmonary Medicine | volume = 16 | issue = 1 | pages = 64–70 | date = January 2010 | pmid = 19844182 | doi = 10.1097/MCP.0b013e3283338fa7 | s2cid = 34157182 }}</ref><ref name=holguin>{{cite journal | vauthors = Holguin F, Fitzpatrick A | title = Obesity, asthma, and oxidative stress | journal = Journal of Applied Physiology | volume = 108 | issue = 3 | pages = 754–9 | date = March 2010 | pmid = 19926826 | doi = 10.1152/japplphysiol.00702.2009 }}</ref> Several factors may be at play including decreased respiratory function due to a buildup of fat and the fact that adipose tissue leads to a pro-inflammatory state.<ref name="Woods 2009">{{cite journal | vauthors = Wood LG, Gibson PG | title = Dietary factors lead to innate immune activation in asthma | journal = Pharmacology & Therapeutics | volume = 123 | issue = 1 | pages = 37–53 | date = July 2009 | pmid = 19375453 | doi = 10.1016/j.pharmthera.2009.03.015 }}</ref>

[[Beta blocker]] medications such as [[propranolol]] can trigger asthma in those who are susceptible.<ref name="pmid17998992">{{cite journal | vauthors = O'Rourke ST | title = Antianginal actions of beta-adrenoceptor antagonists | journal = American Journal of Pharmaceutical Education | volume = 71 | issue = 5 | pages = 95 | date = October 2007 | pmid = 17998992 | pmc = 2064893 | doi = 10.5688/aj710595 }}</ref> [[Cardioselective beta-blockers]], however, appear safe in those with mild or moderate disease.<ref>{{cite journal | vauthors = Salpeter S, Ormiston T, Salpeter E | title = Cardioselective beta-blockers for reversible airway disease | journal = The Cochrane Database of Systematic Reviews | issue = 4 | pages = CD002992 |year = 2002 | volume = 2011 | pmid = 12519582 | doi = 10.1002/14651858.CD002992 | pmc = 8689715 }}</ref><ref>{{cite journal | vauthors = Morales DR, Jackson C, Lipworth BJ, Donnan PT, Guthrie B | title = Adverse respiratory effect of acute β-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials | journal = Chest | volume = 145 | issue = 4 | pages = 779–786 | date = April 2014 | pmid = 24202435 | doi = 10.1378/chest.13-1235 }}</ref> Other medications that can cause problems in asthmatics are [[angiotensin-converting enzyme inhibitors]], [[Acetylsalicylic acid|aspirin]], and [[NSAIDs]].<ref name="pmid15579370">{{cite journal | vauthors = Covar RA, Macomber BA, Szefler SJ | title = Medications as asthma triggers | journal = Immunology and Allergy Clinics of North America | volume = 25 | issue = 1 | pages = 169–90 | date = February 2005 | pmid = 15579370 | doi = 10.1016/j.iac.2004.09.009 }}</ref> Use of acid-suppressing medication ([[proton pump inhibitors]] and [[H2 blockers]]) during pregnancy is associated with an increased risk of asthma in the child.<ref>{{cite journal | vauthors = Lai T, Wu M, Liu J, Luo M, He L, Wang X, Wu B, Ying S, Chen Z, Li W, Shen H | display-authors = 6 | title = Acid-Suppressive Drug Use During Pregnancy and the Risk of Childhood Asthma: A Meta-analysis | journal = Pediatrics | volume = 141 | issue = 2 | pages = e20170889 | date = February 2018 | pmid = 29326337 | doi = 10.1542/peds.2017-0889 | doi-access = free }}</ref>