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Asclepias tuberosa
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==Toxicity== The plant contains toxic [[glycoside]]s, [[alkaloid]]s and [[Resinoid (perfumery)|resinoids]]. These can cause weakness, seizures and [[cornea]]l injuries.<ref>Multiple sources: * {{Cite book|last1=Elias|first1=Thomas S.|url=https://www.worldcat.org/oclc/244766414|title=Edible Wild Plants: A North American Field Guide to Over 200 Natural Foods|last2=Dykeman|first2=Peter A.|publisher=[[Sterling Publishing|Sterling]]|year=2009|isbn=978-1-4027-6715-9|location=New York|pages=267β68|oclc=244766414|orig-year=1982}} * {{cite journal|first1=Lauge Hjorth|last1=Mikkelsen|first2=Hassan|last2=Hamoudi|first3=Cigdem|last3=Altuntas GΓΌl|first4=Steffen|last4=Heegaard|title=Corneal Toxicity Following Exposure to ''Asclepias tuberosa''|journal=The Open Ophthalmology Journal|year=2017|volume=11|pages=1β4|pmid=28400886|pmc=5362972|doi= 10.2174/1874364101711010001 |doi-access=free|publisher=[[Bentham Science Publishers]]|quote=The latex of ''A. tuberosa'' seems to be different from other members of the ''Asclepias'' family due to the fact that even though cardenolides are normally considered present in ''Asclepias'' species, these cardenolides have not been found in ''A. tuberosa''. Instead some unique [[pregnane]] glycosides are found in ''A. tuberosa''.}} * {{cite web|first=Michelle|last=Stevens|url=https://plants.usda.gov/DocumentLibrary/plantguide/pdf/cs_astu.pdf|title=Plant guide for Butterfly Milkweed: Asclepias tuberosa L.|publisher=[[United States Department of Agriculture]]: [[Natural Resources Conservation Service]]: National Plant Data Center|access-date=July 5, 2021|archive-url=https://web.archive.org/web/20210709193453/https://plants.usda.gov/DocumentLibrary/plantguide/pdf/cs_astu.pdf|archive-date=July 9, 2021|url-status=live|quote=Milkweed species, as a group, are known to contain cardiac glycosides that are poisonous both to humans and to livestock, as well as other substances that may account for their medicinal effect. Resinoids, glycosides, and a small amount of alkaloids are present in all parts of the plant. Symptoms of poisoning by the cardiac glycosides include dullness, weakness, bloating, inability to stand or walk, high body temperature, rapid and weak pulse, difficulty breathing, dilated pupils, spasms, and coma.}}</ref> Use of the plant is [[contraindicated]] in pregnancy, during [[lactation]] or with infants due to its toxins, which include resinoids and [[pregnanes]].<ref>Multiple sources: * {{NPIN|ASTU}} "Warning: POISONOUS PARTS: Roots, plant sap from all parts. Not edible. Toxic only if eaten in large quantities. Symptoms include vomiting, stupor, weakness, spasms. Toxic Principle: Resinoid, cardiac glycoside" {{Cite web |title=Lady Bird Johnson Wildflower Center - the University of Texas at Austin |url=https://www.wildflower.org/plants/result.php?id_plant=ASTU |url-status=bot: unknown |archive-url=https://web.archive.org/web/20200205230025/https://www.wildflower.org/plants/result.php?id_plant=ASTU |archive-date=February 5, 2020 |access-date=October 17, 2020}}. * {{cite journal |last1=Mikkelsen |first1=Lauge Hjorth |last2=Hamoudi |first2=Hassan |last3=Altuntas GΓΌl |first3=Cigdem |last4=Heegaard |first4=Steffen |year=2017 |title=Corneal Toxicity Following Exposure to ''Asclepias tuberosa'' |journal=The Open Ophthalmology Journal |publisher=[[Bentham Science Publishers]] |volume=11 |pages=1β4 |doi= 10.2174/1874364101711010001 |doi-access=free|pmc=5362972 |pmid=28400886 |quote=The latex of ''A. tuberosa'' seems to be different from other members of the ''Asclepias'' family due to the fact that even though cardenolides are normally considered present in ''Asclepias'' species, these cardenolides have not been found in ''A. tuberosa''. Instead some unique [[pregnane]] glycosides are found in ''A. tuberosa''.}} * {{cite journal |last1=Warashina |first1=Tsutomu |last2=Noro |first2=Tadataka |date=February 2010 |title=8,12;8,20-Diepoxy-8,14-secopregnane Glycosides from the Aerial Parts of ''Asclepias tuberosa'' |url=https://www.jstage.jst.go.jp/article/cpb/58/2/58_2_172/_pdf/-char/en |journal=[[Chemical and Pharmaceutical Bulletin]] |publisher=Pharmaceutical Society of Japan |volume=58 |issue=2 |pages=172β179 |doi=10.1248/cpb.58.172 |pmid=20118575 |access-date=September 11, 2020 |doi-access=free}}</ref>
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