Editing Action potential (section)

==="All-or-none" principle===
{{Main|All-or-none law}}
The [[amplitude]] of an action potential is often thought to be independent of the amount of current that produced it. In other words, larger currents do not create larger action potentials. Therefore, action potentials are said to be [[All-or-none law|all-or-none]] signals, since either they occur fully or they do not occur at all.<ref name=" Sasaki " group=lower-alpha>Sasaki, T., Matsuki, N., Ikegaya, Y. 2011 Action-potential modulation during axonal conduction Science 331 (6017), pp. 599–601</ref><ref name="Aur" group=lower-alpha>{{cite journal | vauthors = Aur D, Connolly CI, Jog MS | title = Computing spike directivity with tetrodes | journal = Journal of Neuroscience Methods | volume = 149 | issue = 1 | pages = 57–63 | date = November 2005 | pmid = 15978667 | doi = 10.1016/j.jneumeth.2005.05.006 | s2cid = 34131910 }}</ref><ref name="Aur, Jog" group=lower-alpha>Aur D., Jog, MS., 2010 Neuroelectrodynamics: Understanding the brain language, IOS Press, 2010. {{doi|10.3233/978-1-60750-473-3-i}}</ref> This is in contrast to [[receptor potential]]s, whose amplitudes are dependent on the intensity of a stimulus.{{sfn|Purves|Augustine|Fitzpatrick|Hall|2008|pp=26–28}} In both cases, the [[frequency]] of action potentials is correlated with the intensity of a stimulus.

Despite the classical view of the action potential as a stereotyped, uniform signal having dominated the field of neuroscience for many decades, newer evidence does suggest that action potentials are more complex events indeed capable of transmitting information through not just their amplitude, but their duration and phase as well, sometimes even up to distances originally not thought to be possible.<ref>{{cite journal |title=Myelination Increases the Spatial Extent of Analog Modulation of Synaptic Transmission: A Modeling Study |url=https://www.researchgate.net/publication/339655307|journal=Frontiers in Cellular Neuroscience}}</ref><ref>{{cite journal |title=Past and Future of Analog-Digital Modulation of Synaptic Transmission |year=2019 |pmc=6492051 |last1=Zbili |first1=M. |last2=Debanne |first2=D. |journal=Frontiers in Cellular Neuroscience |volume=13 |page=160 |doi=10.3389/fncel.2019.00160 |pmid=31105529 |doi-access=free }}</ref><ref>{{cite journal |title=Neural Coding: Analog Signalling in Axons | journal=Current Biology | date=8 August 2006 | volume=16 | issue=15 | pages=R585–R588 | doi=10.1016/j.cub.2006.07.007 | last1=Clark | first1=Beverley | last2=Häusser | first2=Michael | pmid=16890514 | s2cid=8295969 | doi-access=free }}</ref><ref>{{cite journal |title=Analog transmission of action potential fine structure in spiral ganglion axons |year=2021 |doi=10.1152/jn.00237.2021 |last1=Liu |first1=Wenke |last2=Liu |first2=Qing |last3=Crozier |first3=Robert A. |last4=Davis |first4=Robin L. |journal=Journal of Neurophysiology |volume=126 |issue=3 |pages=888–905 |pmid=34346782 |pmc=8461829 }}</ref>