Jump to content
Main menu
Main menu
move to sidebar
hide
Navigation
Main page
Recent changes
Random page
Help about MediaWiki
Special pages
Niidae Wiki
Search
Search
Appearance
Create account
Log in
Personal tools
Create account
Log in
Pages for logged out editors
learn more
Contributions
Talk
Editing
Acetylcholine
(section)
Page
Discussion
English
Read
Edit
View history
Tools
Tools
move to sidebar
hide
Actions
Read
Edit
View history
General
What links here
Related changes
Page information
Appearance
move to sidebar
hide
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
====Memory==== Acetylcholine has been implicated in [[learning]] and [[memory]] in several ways. The anticholinergic drug [[scopolamine]] impairs acquisition of new information in humans<ref name="pmid4793334">{{cite journal | vauthors = Crow TJ, Grove-White IG | title = An analysis of the learning deficit following hyoscine administration to man | journal = Br. J. Pharmacol. | volume = 49 | issue = 2 | pages = 322β7 | date = October 1973 | pmid = 4793334 | pmc = 1776392 | doi = 10.1111/j.1476-5381.1973.tb08379.x }}</ref> and animals.<ref name="pmid6431311"/> In animals, disruption of the supply of acetylcholine to the [[neocortex]] impairs the learning of simple discrimination tasks, comparable to the acquisition of factual information<ref name="pmid3087582">{{cite journal | vauthors = Ridley RM, Murray TK, Johnson JA, Baker HF | title = Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: modification by cholinergic drugs | journal = Brain Res. | volume = 376 | issue = 1 | pages = 108β16 | date = June 1986 | pmid = 3087582 | doi = 10.1016/0006-8993(86)90904-2 | s2cid = 29182517 }}</ref> and disruption of the supply of acetylcholine to the [[hippocampus]] and adjacent cortical areas produces forgetfulness, comparable to [[anterograde amnesia]] in humans.<ref name="pmid12050084">{{cite journal | vauthors = Easton A, Ridley RM, Baker HF, Gaffan D | title = Unilateral lesions of the cholinergic basal forebrain and fornix in one hemisphere and inferior temporal cortex in the opposite hemisphere produce severe learning impairments in rhesus monkeys | journal = Cereb. Cortex | volume = 12 | issue = 7 | pages = 729β36 | date = July 2002 | pmid = 12050084 | doi = 10.1093/cercor/12.7.729 | doi-access = free }}</ref>
Summary:
Please note that all contributions to Niidae Wiki may be edited, altered, or removed by other contributors. If you do not want your writing to be edited mercilessly, then do not submit it here.
You are also promising us that you wrote this yourself, or copied it from a public domain or similar free resource (see
Encyclopedia:Copyrights
for details).
Do not submit copyrighted work without permission!
Cancel
Editing help
(opens in new window)
Search
Search
Editing
Acetylcholine
(section)
Add topic