Editing Trypanosomatida (section)

=== {{Anchor|Kinetoplastibacterium}}Bacterial endosymbiont ===
{{Automatic taxobox|name=''Kinetoplastibacterium''|taxon=Kinetoplastibacterium|authority=Du et al., 1994}}
Six species of trypanosomatids are known to carry an additional proteobacterial [[endosymbiont]], termed TPE (trypanosomatid proteobacterial endosymbionts). These trypansomatids (''[[Strigomonas oncopelti]]'', ''[[Strigomonas culicis|S. culicis]]'', ''[[Strigomonas galati|S. galati]]'', ''[[Angomonas desouzai]]'', and ''[[Angomonas deanei|A. deanei]]'') are in turn known as SHTs, for symbiont-harboring trypanosomatids. All such symbionts have a shared evolutionary origin and are classified in the [[Candidatus]] genus "'''Kinetoplastibacterium'''".<ref name="pmid23345457">{{cite journal | last1=Alves |first1=JM |last2=Serrano |first2=MG |last3=Maia da Silva |first3=F |last4=Voegtly |first4=LJ |last5=Matveyev |first5=AV |last6=Teixeira |first6=MM |last7=Camargo |first7=EP |last8=Buck |first8=GA | journal = Genome Biology and Evolution |date=2013 |volume=5 |issue=2 |pages=338–50 |doi=10.1093/gbe/evt012 |doi-access=free |pmid=23345457|pmc=3590767 |title=Genome evolution and phylogenomic analysis of ''Candidatus'' Kinetoplastibacterium, the betaproteobacterial endosymbionts of ''Strigomonas'' and ''Angomonas'' }}</ref>

As with many symbionts, the bacteria have a much reduced genome compared to their free-living relatives of genera ''[[Taylorella]]'' and ''[[Achromobacter]]''. ([[GTDB]] finds the genus sister to ''[[Proftella]]'', a symbiont of ''[[Diaphorina citri]]''.)<ref>{{cite web |title=GTDB - Tree at g__Kinetoplastibacterium |url=https://gtdb.ecogenomic.org/tree?r=g__Kinetoplastibacterium |website=gtdb.ecogenomic.org |access-date=2022-12-20 |archive-date=2022-12-20 |archive-url=https://web.archive.org/web/20221220182712/https://gtdb.ecogenomic.org/tree?r=g__Kinetoplastibacterium |url-status=live }}</ref> Reflecting their inability to live alone, they have lost genes dedicated to essential biological functions, relying on the host instead. They have modified their division to become synchronized with the host. In ''S. culicis'' at least, the TPE helps the host by synthesizing [[heme]]<ref name="pmid23345457"/> and producing essential enzymes, staying tethered to the [[kinetoplast]].<ref name=":4">{{Cite journal|last1=de Souza|first1=W.|last2=Motta|first2=M. C.|date=1999|title=Endosymbiosis in protozoa of the Trypanosomatidae family|journal=FEMS Microbiology Letters|volume=173|issue=1|pages=1–8|doi=10.1111/j.1574-6968.1999.tb13477.x|pmid=10220875|doi-access=free}}</ref>
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