Editing Serotonin syndrome (section)

===Agitation===
Specific treatment for some symptoms may be required. One of the most important treatments is the control of agitation due to the extreme possibility of injury to the person themselves or caregivers, benzodiazepines should be administered at first sign of this.<ref name=Boy2005/> [[Medical restraint|Physical restraints]] are not recommended for agitation or delirium as they may contribute to mortality by enforcing isometric [[muscle contraction]]s that are associated with severe [[lactic acidosis]] and hyperthermia. If physical restraints are necessary for severe agitation they must be rapidly replaced with pharmacological [[sedation]].<ref name=Boy2005/> The agitation can cause a large amount of muscle breakdown. This breakdown can cause severe damage to the kidneys through a condition called [[rhabdomyolysis]].<ref>{{cite web |url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004531/ |title=Serotonin syndrome – PubMed Health |publisher=Ncbi.nlm.nih.gov |access-date=2013-01-28 |url-status=live |archive-url=https://web.archive.org/web/20130201070649/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004531/ |archive-date=2013-02-01 }}</ref>