Editing Scabies (section)

==Pathophysiology==
The symptoms are caused by an [[allergic reaction]] of the host's body to mite proteins, though exactly which proteins remains a topic of study. The mite proteins are also present in the gut, and in mite feces, which are deposited under the skin. The allergic reaction is both of the delayed (cell-mediated) and immediate (antibody-mediated) type, and involves IgE (antibodies are presumed to mediate the very rapid symptoms on reinfection).<ref name=autogenerated1>{{cite journal | vauthors = Walton SF, Currie BJ | title = Problems in diagnosing scabies, a global disease in human and animal populations | journal = Clinical Microbiology Reviews | volume = 20 | issue = 2 | pages = 268–279 | date = April 2007 | pmid = 17428886 | pmc = 1865595 | doi = 10.1128/CMR.00042-06 }}</ref> The allergy-type symptoms (itching) continue for some days, and even several weeks, after all mites are killed. New lesions may appear for a few days after mites are eradicated. Nodular lesions from scabies may continue to be symptomatic for weeks after the mites have been killed.<ref name=autogenerated1 />

Rates of scabies are negatively related to temperature and positively related to humidity.<ref name="LiuWang2016">{{cite journal | vauthors = Liu JM, Wang HW, Chang FW, Liu YP, Chiu FH, Lin YC, Cheng KC, Hsu RJ | title = The effects of climate factors on scabies. A 14-year population-based study in Taiwan | journal = Parasite | volume = 23 | pages = 54 | year = 2016 | pmid = 27905271 | pmc = 5134670 | doi = 10.1051/parasite/2016065 }} {{open access}}</ref>