Editing Protein quaternary structure (section)

==Structure Prediction==
Some bioinformatics methods have been developed for predicting the quaternary structural attributes of proteins based on their sequence information by using various modes of [[pseudo amino acid composition]].<ref name="Predicting protein quaternary struc"/><ref>{{cite journal | vauthors = Zhang SW, Chen W, Yang F, Pan Q | title = Using Chou's pseudo amino acid composition to predict protein quaternary structure: a sequence-segmented PseAAC approach | journal = Amino Acids | volume = 35 | issue = 3 | pages = 591–598 | date = October 2008 | pmid = 18427713 | doi = 10.1007/s00726-008-0086-x | s2cid = 689955 }}</ref><ref>{{cite journal | vauthors = Xiao X, Wang P, Chou KC |year=2009 |title=Predicting protein quaternary structural attribute by hybridizing functional domain composition and pseudo amino acid composition |journal=Journal of Applied Crystallography |volume=42 |pages=169–173 |doi=10.1107/S0021889809002751 }}</ref>

Protein folding prediction programs used to predict protein tertiary structure have also been expanding to better predict protein quaternary structure. One such development is AlphaFold-Multimer<ref>{{Cite journal| vauthors = Evans R, O'Neill M, Pritzel A, Antropova N, Senior AW, Green T, Žídek A, Bates R, Blackwell S, Yim J, Ronneberger O | display-authors = 6 |date=2021-10-04|title=Protein complex prediction with AlphaFold-Multimer | journal = bioRxiv|url=https://www.biorxiv.org/content/10.1101/2021.10.04.463034v1 |language=en |pages=2021.10.04.463034 |doi=10.1101/2021.10.04.463034| s2cid = 238413014 }}</ref> built upon the [[AlphaFold]] model for predicting protein tertiary structure.