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===Ultraspice=== <!-- This section is the redirect destination of [[ultraspice]] --> In ''[[Sandworms of Dune]]'', Brian Herbert and Anderson's 2007 conclusion to the original series, the Spacing Guild is manipulated into replacing its Navigators with [[Ix (Dune)|Ixian]] navigation devices and cutting off the Navigators' supply of melange. Sure to die should they be without the spice, a group of Navigators commission [[Tylwyth Waff|Waff]], an imperfectly awakened Tleilaxu ghola, to create "advanced" sandworms able to produce the melange they so desperately require. He accomplishes this by altering the [[DNA]] of the worm's sandtrout stage and creating an aquatic form of the worms, which are then released into the oceans of [[Buzzell (Dune)|Buzzell]]. Adapting to their new environment, these "[[seaworm]]s" quickly flourish, eventually producing a highly concentrated form of spice, dubbed '''ultraspice'''. This new form of spice is so powerful that a relatively small dose causes a potential [[Kwisatz Haderach]] to descend into a complete and unbreakable coma through perfect prescience.<ref name="Sandworms">{{cite book |last1=Herbert |first1=Brian |first2=Kevin J. |last2=Anderson |title=[[Sandworms of Dune]] |year=2007}}</ref>
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