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==Complications== Complications from the viral infections that cause HFMD are rare but require immediate medical treatment if present. HFMD infections caused by [[Enterovirus 71]] tend to be more severe and are more likely to have neurologic or cardiac complications including death than infections caused by Coxsackievirus A16.<ref name=Sar2013/> Viral or [[aseptic meningitis]] can occur with HFMD in rare cases and is characterized by fever, [[headache]], [[neck stiffness|stiff neck]], or back pain.<ref name=PLOS2012/><ref name=Sar2013/> The condition is usually mild and clears without treatment; however, hospitalization for a short time may be needed. Other serious complications of HFMD include [[encephalitis]] (inflammation of the brain), or [[flaccid paralysis]] in rare circumstances.<ref name="Huang1999"/><ref name=Sar2013/> [[Onychomadesis|Fingernail and toenail loss]] have been reported in children 4β8 weeks after having HFMD.<ref name=Hoy2012/> The relationship between HFMD and the reported nail loss is unclear; however, it is temporary and nail growth resumes without treatment.<ref name=Hoy2012/><ref>{{cite web |url=https://www.cdc.gov/hand-foot-mouth/about/complications.html |title=Hand, Foot and Mouth Disease |year=2011 |work=Complications |publisher=Centers for Disease Control and Prevention |access-date=October 14, 2013 |url-status=live |archive-url=https://web.archive.org/web/20131017093341/http://www.cdc.gov/hand-foot-mouth/about/complications.html |archive-date=October 17, 2013 }}</ref> Minor complications due to symptoms can occur such as dehydration, due to mouth sores causing discomfort with intake of foods and fluid.<ref name=":0">{{Cite web|url=http://www.wpro.who.int/mediacentre/factsheets/fs_10072012_HFMD/en/|archive-url=https://web.archive.org/web/20140424065042/http://www.wpro.who.int/mediacentre/factsheets/fs_10072012_HFMD/en/|url-status=dead|archive-date=April 24, 2014|title=Hand, Foot and Mouth Disease|website=WHO Western Pacific Region|language=en-GB|access-date=November 6, 2017}}</ref>
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