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=== Others === * [[Opioid receptor]] agonists are primarily utilized for their analgesic effects. These drugs, however, can also elicit sedation. This effect is mediated by opioid actions on both opioid and acetylcholine receptors. While these drugs can lead to decreased arousal, they do not elicit a loss of consciousness. For this reason, they are often used in parallel with other general anesthetics to help maintain a state of general anesthesia. Such drugs include [[morphine]], [[fentanyl]], [[hydromorphone]], and [[remifentanil]].<ref name=":04" /><ref name=":25" /> * Administration of the [[Adrenergic receptor|alpha2 adrenergic receptor]] agonist [[dexmedetomidine]] leads to sedation that resembles [[non-REM]] sleep. It is used in parallel with other general anesthetics to help maintain a state of general anesthesia, in an off-label capacity. Notably, patients are easily aroused from this non-REM sleep state.<ref name=":04" /><ref name=":16" /><ref name=":25" /> * [[Dopamine receptor]] antagonists have sedative and [[antiemetic]] properties. Previously, they were used in parallel with opioids to elicit neuroleptic anesthesia ([[catalepsy]], analgesia, and unresponsiveness). They are no longer used in the context, because patients experiencing neuroleptic anesthesia were frequently aware of the medical procedures being performed, but could not move or express emotion. Such drugs include [[haloperidol]] and [[droperidol]].<ref name=":04" />
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