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=== Sweetness of fructose === {{See also|Sweetness#Examples of sweet substances}} The primary reason that fructose is used commercially in foods and beverages, besides its low cost, is its high relative sweetness. It is the sweetest of all naturally occurring [[carbohydrate]]s. The relative sweetness of fructose has been reported in the range of 1.2β1.8 times that of sucrose.<ref name=Hanover>{{cite journal|last1=Hanover|first1=L. M.| last2= White| first2=J. S.|title=Manufacturing, composition, and applications of fructose |journal= [[The American Journal of Clinical Nutrition]]| via= nutrition.org |date=1 November 1993 |volume= 58 |issue=5 |pages= 724Sβ732S| url=http://ajcn.nutrition.org/content/58/5/724S.abstract|access-date=7 February 2017| language=en |issn= 0002-9165 |url-status= live |archive-url= https://web.archive.org/web/20160414002156/http://ajcn.nutrition.org/content/58/5/724S.abstract|archive-date=14 April 2016|doi=10.1093/ajcn/58.5.724S|pmid=8213603|doi-access=free}}</ref><ref name= "Oregon State University">{{cite web| publisher= Oregon State University| title= Sugar Sweetness| url= http://food.oregonstate.edu/sugar/sweet.html |archiveurl= https://web.archive.org/web/20080516050325/http://food.oregonstate.edu/sugar/sweet.html| website= food.oregonstate.edu |archivedate=May 16, 2008 |accessdate=7 February 2017}}</ref><ref name="Kirk-Othmer">{{cite book| last1= Lee|first1=Thomas D.| chapter= Sweeteners| title= Kirk-Othmer Encyclopedia of Chemical Technology|date=1 January 2000| doi= 10.1002/0471238961.19230505120505.a01.pub2 |language= en|isbn=978-0471238966}}</ref><ref>{{cite journal |last1=Jana| first1=A.H. |last2=Joshi |first2= N.S.S.| title= Sweeteners for frozen [desserts] success β a review |journal= [[Australian Journal of Dairy Technology]] |date=November 1994|volume=49|url=http://agris.fao.org/agris-search/search.do?recordID=AU9500465|access-date=7 February 2017 |url-status= live| archive-url=https://web.archive.org/web/20170208033252/http://agris.fao.org/agris-search/search.do?recordID=AU9500465|archive-date=8 February 2017}}</ref> However, it is the 6-membered ring form of fructose that is sweeter; the 5-membered ring form tastes about the same as usual table sugar. Warming fructose leads to formation of the 5-membered ring form.<ref>{{cite book | title=Taste Chemistry| last=Shallenberger| first=R.S.| year=1994| publisher=Chapman and Hall | isbn=978-0-7514-0150-9}}</ref> Therefore, the relative sweetness decreases with increasing temperature. However, it has been observed that the absolute sweetness of fructose is identical at 5 Β°C as 50 Β°C and thus the relative sweetness to sucrose is not due to [[anomeric]] distribution but a decrease in the absolute sweetness of sucrose at higher temperatures.<ref name="Kirk-Othmer"/> [[File:Relativesweetness.svg|thumb|center|400px|Relative sweetness of sugars and sweeteners]] The sweetness of fructose is perceived earlier than that of sucrose or glucose, and the taste sensation reaches a peak (higher than that of sucrose), and diminishes more quickly than that of sucrose. Fructose can also enhance other flavors in the system.<ref name=Hanover /><ref name="Kirk-Othmer"/> Fructose exhibits a sweetness synergy effect when used in combination with other sweeteners. The relative sweetness of fructose blended with sucrose, aspartame, or saccharin is perceived to be greater than the sweetness calculated from individual components.<ref name=Nabors>{{cite book | last=Nabors | first=LO | title =American Sweeteners | year=2001 | pages=374β375}}</ref><ref name="Kirk-Othmer"/>
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