Editing Fibronectin (section)

== Interactions ==
Besides integrin, fibronectin binds to many other host and non-host molecules. For example, it has been shown to interact with proteins such [[fibrin]], [[tenascin]], TNF-α, BMP-1, rotavirus NSP-4, and many fibronectin-binding proteins from bacteria (like FBP-A; FBP-B on the N-terminal domain), as well as the [[glycosaminoglycan]], [[heparan sulfate]].

Fibronectin has been shown to [[Protein-protein interaction|interact]] with:
* [[CD44]]<ref name="pmid1730778">{{cite journal | vauthors = Jalkanen S, Jalkanen M | title = Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin | journal = The Journal of Cell Biology | volume = 116 | issue = 3 | pages = 817–25 | date = Feb 1992 | pmid = 1730778 | pmc = 2289325 | doi = 10.1083/jcb.116.3.817 }}</ref>
* [[Collagen, type VII, alpha 1|COL7A1]],<ref name="pmid7963647">{{cite journal | vauthors = Lapiere JC, Chen JD, Iwasaki T, Hu L, Uitto J, Woodley DT | title = Type VII collagen specifically binds fibronectin via a unique subdomain within the collagenous triple helix | journal = The Journal of Investigative Dermatology | volume = 103 | issue = 5 | pages = 637–41 | date = Nov 1994 | pmid = 7963647 | doi = 10.1111/1523-1747.ep12398270 | doi-access =  }}</ref><ref name="pmid9169408">{{cite journal | vauthors = Chen M, Marinkovich MP, Veis A, Cai X, Rao CN, O'Toole EA, Woodley DT | title = Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin | journal = The Journal of Biological Chemistry | volume = 272 | issue = 23 | pages = 14516–22 | date = Jun 1997 | pmid = 9169408 | doi = 10.1074/jbc.272.23.14516 | doi-access = free }}</ref>
* [[Lipoprotein(a)|LPA]],<ref name="pmid2531657">{{cite journal | vauthors = Salonen EM, Jauhiainen M, Zardi L, Vaheri A, Ehnholm C | title = Lipoprotein(a) binds to fibronectin and has serine proteinase activity capable of cleaving it | journal = The EMBO Journal | volume = 8 | issue = 13 | pages = 4035–40 | date = Dec 1989 | pmid = 2531657 | pmc = 401578 | doi =  10.1002/j.1460-2075.1989.tb08586.x}}</ref>
* [[IGFBP3]],<ref name="pmid12127836">{{cite journal | vauthors = Martin JA, Miller BA, Scherb MB, Lembke LA, Buckwalter JA | title = Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage | journal = Osteoarthritis and Cartilage | volume = 10 | issue = 7 | pages = 556–63 | date = Jul 2002 | pmid = 12127836 | doi = 10.1053/joca.2002.0791 | doi-access = free }}</ref><ref name="pmid11344214">{{cite journal | vauthors = Gui Y, Murphy LJ | title = Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) binds to fibronectin (FN): demonstration of IGF-I/IGFBP-3/fn ternary complexes in human plasma | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 86 | issue = 5 | pages = 2104–10 | date = May 2001 | pmid = 11344214 | doi = 10.1210/jcem.86.5.7472 | doi-access = free }}</ref>
* [[Tenascin C|TNC]],<ref name="pmid7499434">{{cite journal | vauthors = Chung CY, Zardi L, Erickson HP | title = Binding of tenascin-C to soluble fibronectin and matrix fibrils | journal = The Journal of Biological Chemistry | volume = 270 | issue = 48 | pages = 29012–7 | date = Dec 1995 | pmid = 7499434 | doi = 10.1074/jbc.270.48.29012 | doi-access = free }}</ref> and
* [[TRIB3]].<ref name="pmid18276110">{{cite journal | vauthors = Zhou Y, Li L, Liu Q, Xing G, Kuai X, Sun J, Yin X, Wang J, Zhang L, He F | title = E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3 | journal = Cellular Signalling | volume = 20 | issue = 5 | pages = 942–8 | date = May 2008 | pmid = 18276110 | doi = 10.1016/j.cellsig.2008.01.010 }}</ref>