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=== Role in human carcinoma === Some research has suggested that a deregulation of cAMP pathways and an aberrant activation of cAMP-controlled genes is linked to the growth of some cancers.<ref>{{cite journal| url = http://cancerres.aacrjournals.org/cgi/content/full/64/4/1338| title = American Association for Cancer Research (cAMP-responsive Genes and Tumor Progression)| journal = Cancer Research| date = 15 February 2004| volume = 64| issue = 4| pages = 1338β1346| doi = 10.1158/0008-5472.CAN-03-2089| last1 = Abramovitch| first1 = Rinat| last2 = Tavor| first2 = Einat| last3 = Jacob-Hirsch| first3 = Jasmine| last4 = Zeira| first4 = Evelyne| last5 = Amariglio| first5 = Ninette| last6 = Pappo| first6 = Orit| last7 = Rechavi| first7 = Gideon| last8 = Galun| first8 = Eithan| last9 = Honigman| first9 = Alik| pmid = 14973073| s2cid = 14047485}}</ref><ref>{{cite journal| url = http://cancerres.aacrjournals.org/cgi/content/abstract/66/19/9483| title = American Association for Cancer Research (cAMP Dysregulation and Melonoma)| journal = Cancer Research| date = October 2006| volume = 66| issue = 19| pages = 9483β9491| doi = 10.1158/0008-5472.CAN-05-4227| last1 = Dumaz| first1 = Nicolas| last2 = Hayward| first2 = Robert| last3 = Martin| first3 = Jan| last4 = Ogilvie| first4 = Lesley| last5 = Hedley| first5 = Douglas| last6 = Curtin| first6 = John A.| last7 = Bastian| first7 = Boris C.| last8 = Springer| first8 = Caroline| last9 = Marais| first9 = Richard| pmid = 17018604| doi-access = free}}</ref><ref>{{cite journal| url = http://clincancerres.aacrjournals.org/cgi/content/abstract/2/1/201| title = American Association for Cancer Research (cAMP-binding Proteins' Presence in Tumors)| journal = Clinical Cancer Research| date = January 1996| volume = 2| issue = 1| pages = 201β206| last1 = Simpson| first1 = B. J.| last2 = Ramage| first2 = A. D.| last3 = Hulme| first3 = M. J.| last4 = Burns| first4 = D. J.| last5 = Katsaros| first5 = D.| last6 = Langdon| first6 = S. P.| last7 = Miller| first7 = W. R.}}</ref>
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