Editing Craig Venter (section)

===Individual human genome===
On September 4, 2007, a team led by Sam Levy published one of the first genomes of an individual human—Venter's own DNA sequence.<ref name="Kirkness, Ewen F.-2007">{{cite journal|journal=PLOS Biology|date=2007|volume=5|issue=10|title=The Diploid Genome Sequence of an Individual Human|author=Levy S | doi = 10.1371/journal.pbio.0050254|pages=e254|pmid=17803354|pmc=1964779|author2=Sutton G|author3=Ng PC|author4=Feuk L|author5=Halpern AL|display-authors=5|last6=Walenz|first6=Brian P.|last7=Axelrod|first7=Nelson|last8=Huang|first8=Jiaqi|last9=Kirkness|first9=Ewen F. |doi-access=free }}</ref> Some of the sequences in Venter's genome are associated with wet earwax,<ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=117800|title=Omim – Ear Wax, Wet/Dry<!-- Bot generated title -->|website=Ncbi.nlm.mih.gov|access-date=January 5, 2019}}</ref> increased risk of antisocial behavior, [[Alzheimer's disease|Alzheimer's]] and [[cardiovascular diseases]].<ref name="J. Craig Venter-2007"/> 

The Human Reference Genome Browser is a web application for the navigation and analysis of Venter's recently published genome. The HuRef database consists of approximately 32 million DNA reads sequenced using [[microfluidic Sanger sequencing]], assembled into 4,528 scaffolds and 4.1 million [[Mutation|DNA variation]]s identified by genome analysis. These variants include [[single-nucleotide polymorphism]]s (SNPs), block [[point mutation|substitutions]], short and large [[indel]]s, and structural variations like [[insertion (genetics)|insertions]], [[deletion (genetics)|deletions]], [[chromosome inversion|inversions]] and [[copy number variation|copy number changes]].

The browser enables scientists to navigate the HuRef genome assembly and sequence variations, and to compare it with the NCBI human build 36 assembly in the context of the [[National Center for Biotechnology Information|NCBI]] and [[Ensembl]] annotations. The browser provides a comparative view between NCBI and HuRef consensus sequences, the sequence multi-alignment of the HuRef assembly, Ensembl and dbSNP annotations, HuRef variants, and the underlying variant evidence and functional analysis. The interface also represents the [[haplotype]] blocks from which diploid genome sequence can be inferred and the relation of variants to gene annotations. The display of variants and gene annotations are linked to external public resources including [[dbSNP]], Ensembl, [[Online Mendelian Inheritance in Man]] (OMIM) and [[Gene Ontology]] (GO).

Users can search the HuRef genome using HUGO gene names, Ensembl and dbSNP identifiers, HuRef [[contig]] or scaffold locations, or NCBI chromosome locations. Users can then easily and quickly browse any genomic region via the simple and intuitive pan and zoom controls; furthermore, data relevant to specific loci can be exported for further analysis.