Editing Butanone (section)

===Health effects===
Butanone is a constituent of [[tobacco smoke]].<ref name="TalhoutSchulz2011">{{cite journal|last1=Talhout|first1=Reinskje|last2=Schulz|first2=Thomas|last3=Florek|first3=Ewa|last4=Van Benthem|first4=Jan|last5=Wester|first5=Piet|last6=Opperhuizen|first6=Antoon|title=Hazardous Compounds in Tobacco Smoke|journal=International Journal of Environmental Research and Public Health|volume=8|issue=12|year=2011|pages=613–628|issn=1660-4601|doi=10.3390/ijerph8020613|pmid=21556207|pmc=3084482|doi-access=free}}</ref> It is an [[irritation|irritant]], causing irritation to the eyes and nose of humans.<ref name="Fairhall"/>  Serious animal health effects have been seen only at very high levels. There are no long-term studies with animals breathing or drinking it,<ref name=iris>{{cite web|title=Methyl ethyl ketone (MEK) (CASRN 78-93-3)|url=http://www.epa.gov/iris/subst/0071.htm|website=Integrated Risk Information System (IRIS)|publisher=EPA|access-date=16 March 2015|date=26 September 2003}}</ref> and no studies for carcinogenicity in animals breathing or drinking it.<ref name=tox>{{cite web|title=US Toxicological review of Methyl ethyl ketone In Support of Summary Information on the Integrated Risk Information System (IRIS)|date= September 2003|url=http://www.epa.gov/iris/toxreviews/0071tr.pdf|publisher=US Environmental Protection Agency|access-date=16 March 2015|pages=152}}</ref>{{rp|96}}
There is some evidence that butanone can [[potentiator|potentiate]] the toxicity of other solvents, in contrast to the calculation of mixed solvent exposures by simply adding exposures.<ref>{{cite journal | doi = 10.1136/oem.2005.022400| title = Solvent neurotoxicity| date = 2006| last1 = Dick| first1 = F. D.| journal = Occupational and Environmental Medicine| volume = 63| issue = 3| pages = 221–226| pmid = 16497867| pmc = 2078137}}</ref>

{{As of|2010}}, the United States Environmental Protection Agency (EPA) listed butanone as a toxic chemical. There are reports of neuropsychological effects. It is rapidly absorbed through undamaged skin and lungs. It contributes to the formation of [[ground-level ozone]], which is [[ground-level ozone#Health effects|toxic in low concentrations]].<ref name=medrev>{{cite journal |archive-url=https://web.archive.org/web/20220121103345/http://www.jofcr.com/jcrarchives/vol28/v28i4thompson.pdf|archive-date=2022-01-21|url=http://www.jofcr.com/jcrarchives/vol28/v28i4thompson.pdf|title=Implications for cognitive rehabilitation and brain injury from exposure to Methyl Ethyl Ketone (MEK): a review|author=Simon B.N. Thompson|journal=Journal of Cognitive Rehabilitation|date=Winter 2010|volume=28(Winter)|pages=4–14}}</ref>