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=== Wildlife trade or animal attacks === The wildlife trade may increase spillover risk because it directly increases the number of interactions across animal species, sometimes in small spaces.<ref>{{cite journal | vauthors = Glidden CK, Nova N, Kain MP, Lagerstrom KM, Skinner EB, Mandle L, Sokolow SH, Plowright RK, Dirzo R, De Leo GA, Mordecai EA | display-authors = 6 | title = Human-mediated impacts on biodiversity and the consequences for zoonotic disease spillover | journal = Current Biology | volume = 31 | issue = 19 | pages = R1342βR1361 | date = October 2021 | pmid = 34637744 | doi = 10.1016/j.cub.2021.08.070 | s2cid = 238588772 | pmc = 9255562 | bibcode = 2021CBio...31R1342G }}</ref> The origin of the [[COVID-19 pandemic]]<ref name="BJC_Beirne2021">{{cite journal | vauthors = You M | title = Changes of China's regulatory regime on commercial artificial breeding of terrestrial wildlife in time of COVID-19 outbreak and impacts on the future | journal = Biological Conservation | volume = 250 | issue = 3 | page = 108756 | date = October 2020 | pmc = 7953978 | doi = 10.1093/bjc/azaa084 | publisher = Oxford University Press | jfm = | zbl = | jstor = | pmid = 32863392 | mr = }}</ref><ref name="CovidAndCapital">{{cite journal | vauthors = Blattner C, Coulter K, Wadiwel D, Kasprzycka E | title = Covid-19 and Capital: Labour Studies and Nonhuman Animals β A Roundtable Dialogue | journal = Animal Studies Journal | volume = 10 | issue = 1 | pages = 240β272 | publisher = University of Wollongong | date = 2021 | url = https://ro.uow.edu.au/asj/vol10/iss1/11/ | jstor = | issn = 2201-3008 | doi = 10.14453/asj.v10i1.10 | id = | mr = | zbl = | jfm = | access-date = 19 September 2021| doi-access = free }}</ref> is traced to the [[wet markets in China]].<ref name="SunEtAl_2020">{{cite journal | vauthors = Sun J, He WT, Wang L, Lai A, Ji X, Zhai X, Li G, Suchard MA, Tian J, Zhou J, Veit M, Su S | display-authors = 6 | title = COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives | journal = Trends in Molecular Medicine | volume = 26 | issue = 5 | pages = 483β495 | date = May 2020 | pmid = 32359479 | pmc = 7118693 | doi = 10.1016/j.molmed.2020.02.008 | name-list-style = vanc }}</ref><ref name="WHOPoints_2021">{{cite news |title=WHO Points To Wildlife Farms In Southern China As Likely Source Of Pandemic |url=https://www.npr.org/sections/goatsandsoda/2021/03/15/977527808/who-points-to-wildlife-farms-in-southwest-china-as-likely-source-of-pandemic?t=1616302540855 |publisher=[[NPR]] |date=15 March 2021}}</ref><ref name="Maxmen_2021">{{cite journal | vauthors = Maxmen A | title = WHO report into COVID pandemic origins zeroes in on animal markets, not labs | journal = Nature | volume = 592 | issue = 7853 | pages = 173β174 | date = April 2021 | pmid = 33785930 | doi = 10.1038/d41586-021-00865-8 | s2cid = 232429241 | bibcode = 2021Natur.592..173M }}</ref><ref>{{Cite journal |last1=Huang |first1=Chaolin |last2=Wang |first2=Yeming |last3=Li |first3=Xingwang |last4=Ren |first4=Lili |last5=Zhao |first5=Jianping |last6=Hu |first6=Yi |last7=Zhang |first7=Li |last8=Fan |first8=Guohui |last9=Xu |first9=Jiuyang |last10=Gu |first10=Xiaoying |last11=Cheng |first11=Zhenshun |last12=Yu |first12=Ting |last13=Xia |first13=Jiaan |last14=Wei |first14=Yuan |last15=Wu |first15=Wenjuan |date=2020-02-15 |title=Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China |journal=Lancet |volume=395 |issue=10223 |pages=497β506 |doi=10.1016/S0140-6736(20)30183-5 |issn=1474-547X |pmc=7159299 |pmid=31986264}}</ref> Zoonotic disease emergence is demonstrably linked to the consumption of wildlife meat, exacerbated by human encroachment into natural habitats and amplified by the unsanitary conditions of wildlife markets.<ref>{{Cite journal |last1=Karesh |first1=William B. |last2=Cook |first2=Robert A. |last3=Bennett |first3=Elizabeth L. |last4=Newcomb |first4=James |date=July 2005 |title=Wildlife trade and global disease emergence |journal=Emerging Infectious Diseases |volume=11 |issue=7 |pages=1000β1002 |doi=10.3201/eid1107.050194 |issn=1080-6040 |pmc=3371803 |pmid=16022772}}</ref><ref>{{Cite web |title=Zoonotic Pathogens in Wildlife Traded in Markets for Human Consumption, Laos |url=https://wwwnc.cdc.gov/eid/404.html?aspxerrorpath=/eid/article/28/4/21-0249_article |access-date=2025-05-15 |website=cdc.gov}}</ref> These markets, where diverse species converge, facilitate the mixing and transmission of pathogens, including those responsible for outbreaks of [[HIV-1 protease|HIV-1]],<ref>{{Cite journal |last1=Hahn |first1=B. H. |last2=Shaw |first2=G. M. |last3=De Cock |first3=K. M. |last4=Sharp |first4=P. M. |date=2000-01-28 |title=AIDS as a zoonosis: scientific and public health implications |journal=Science |volume=287 |issue=5453 |pages=607β614 |doi=10.1126/science.287.5453.607 |issn=0036-8075 |pmid=10649986|bibcode=2000Sci...287..607H }}</ref> [[Ebola]],<ref>{{Cite journal |last1=Leroy |first1=Eric M. |last2=Rouquet |first2=Pierre |last3=Formenty |first3=Pierre |last4=SouquiΓ¨re |first4=Sandrine |last5=Kilbourne |first5=Annelisa |last6=Froment |first6=Jean-Marc |last7=Bermejo |first7=Magdalena |last8=Smit |first8=Sheilag |last9=Karesh |first9=William |last10=Swanepoel |first10=Robert |last11=Zaki |first11=Sherif R. |last12=Rollin |first12=Pierre E. |date=2004-01-16 |title=Multiple Ebola virus transmission events and rapid decline of central African wildlife |journal=Science |volume=303 |issue=5656 |pages=387β390 |doi=10.1126/science.1092528 |issn=1095-9203 |pmid=14726594|bibcode=2004Sci...303..387L |s2cid=43305484 }}</ref> and [[mpox]],<ref>{{Cite journal |last1=Reed |first1=Kurt D. |last2=Melski |first2=John W. |last3=Graham |first3=Mary Beth |last4=Regnery |first4=Russell L. |last5=Sotir |first5=Mark J. |last6=Wegner |first6=Mark V. |last7=Kazmierczak |first7=James J. |last8=Stratman |first8=Erik J. |last9=Li |first9=Yu |last10=Fairley |first10=Janet A. |last11=Swain |first11=Geoffrey R. |last12=Olson |first12=Victoria A. |last13=Sargent |first13=Elizabeth K. |last14=Kehl |first14=Sue C. |last15=Frace |first15=Michael A. |date=2004-01-22 |title=The detection of monkeypox in humans in the Western Hemisphere |journal=The New England Journal of Medicine |volume=350 |issue=4 |pages=342β350 |doi=10.1056/NEJMoa032299 |issn=1533-4406 |pmid=14736926}}</ref> and potentially even the [[COVID-19 pandemic]].<ref>{{Cite journal |last1=Li |first1=Xiaojun |last2=Giorgi |first2=Elena E. |last3=Marichannegowda |first3=Manukumar Honnayakanahalli |last4=Foley |first4=Brian |last5=Xiao |first5=Chuan |last6=Kong |first6=Xiang-Peng |last7=Chen |first7=Yue |last8=Gnanakaran |first8=S. |last9=Korber |first9=Bette |last10=Gao |first10=Feng |date=July 2020 |title=Emergence of SARS-CoV-2 through recombination and strong purifying selection |journal=Science Advances |volume=6 |issue=27 |pages=eabb9153 |doi=10.1126/sciadv.abb9153 |issn=2375-2548 |pmc=7458444 |pmid=32937441|bibcode=2020SciA....6.9153L }}</ref> Notably, small mammals often harbor a vast array of zoonotic bacteria and viruses,<ref>{{Cite journal |last1=Mills |first1=J. N. |last2=Childs |first2=J. E. |date=1998 |title=Ecologic studies of rodent reservoirs: their relevance for human health |journal=Emerging Infectious Diseases |volume=4 |issue=4 |pages=529β537 |doi=10.3201/eid0404.980403 |issn=1080-6040 |pmc=2640244 |pmid=9866729}}</ref> yet endemic bacterial transmission among wildlife remains largely unexplored. Therefore, accurately determining the pathogenic landscape of traded wildlife is crucial for guiding effective measures to combat zoonotic diseases and documenting the societal and environmental costs associated with this practice. * [[Rabies]]
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