Editing U.S. Route 22 (section)

==Major intersections==
{{Further|U.S. Route 22 in Pennsylvania#Major intersections|U.S. Route 22 in New Jersey#Major intersections}}
{{jcttop|exit|state_col=state|length_ref=<ref name=length>{{cite web |author=Division of Planning, Office of Technical Services |title=DESTAPE |url=http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Pages/DESTAPE.aspx |publisher=[[Ohio Department of Transportation]] |date=August 30, 2017 |access-date=February 19, 2020}}
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESHAM.pdf Hamilton County], pp. 5-10
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESWAR.pdf Warren County], pp. 1-3
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESCLI.pdf Clinton County], pp. 1-4
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESFAY.pdf Fayette County], pp. 1-3
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESPIC.pdf Pickaway County], pp. 1-3
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESFAI.pdf Fairfield County], pp. 1-3
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESPER.pdf Perry County], pp. 4-5
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESMUS.pdf Muskingum County], pp. 1-6
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESGUE.pdf Guernsey County], pp. 1-5
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESHAS.pdf Harrison County], pp. 3-5
*[http://www.dot.state.oh.us/Divisions/Planning/TechServ/TIM/Documents/DESTAPECnty/DESJEF.pdf Jefferson County], pp. 4-5
</ref><ref name=wv-length>{{google maps |url=https://www.google.com/maps/dir/40.3766038,-80.6117989/40.3993486,-80.5179784/@40.3880994,-80.5924735,13.59z/am=t/data=!4m2!4m1!3e0 |title=U.S. Route 22 |access-date=February 19, 2020}}</ref>}}
{{OHint|exit
|sspan=85
|county=Hamilton
|cspan=16
|location=Cincinnati
|lspan=9
|mile=0.00
|type=concur
|road={{jct|state=OH|US|27|US|42|US|52|US|127|dir1=south|dir2=south|dir3=east|dir4=south|name4=Central Avenue|road|5th Street West}}
|notes=Western terminus of US 27 / US 42 south / US 52 / US 127 [[concurrency (road)|concurrency]]; southern terminus of SR 3
}}
{{OHint|exit
|mile=0.09
|road={{jct|state=OH|US|50|dir1=west|SR|264|dir2=west|name2=Sixth Street West|I|75|dir3=north}}
|notes=Eastern terminus of SR 264; western terminus of [[one-way pair]]; exit 1E on I-75 south
|espan=70
}}
{{OHint
|mile=0.17
|type=concur
|road={{jct|state=OH|US|27|US|52|US|127|dir1=north|dir2=west|dir3=north|name3=Central Avenue|road|7th Street West}}
|notes=Eastern terminus of US 27 / US 42 south / US 52 / US 127 concurrency
}}
{{OHint
|mile=0.33
|road={{jctname|state=OH|US|42|noshield1=yes|dir1=north|name1=Elm Street}}
}}
{{OHint
|mile=0.87
|road=Broadway Street
|notes=Eastern terminus of [[one-way pair]]
}}
{{OHint
|mile=1.26
|type=incomplete
|road={{jct|state=OH|I|71|dir1=north|city1=Columbus}}
|notes=Northbound exit only; exit 2B on I-71 south
}}
{{OHint
|mile=1.58
|road={{jct|state=OH|road|Elsinore Place|I|471|I|71|dir3=north|to2=yes}}
|notes=To [[US 42 (OH)|US 42]]
}}
{{OHint
|mile=1.89
|road={{jct|state=OH|road|Eden Park Drive|I|471|I|71|dir3=south|to2=yes}}
}}
{{OHint
|mile=4.49
|road={{jct|state=OH|I|71|dir1=south|location1=[[Louisville, Kentucky|Louisville]]}}
|notes=Exit 5 on I-71 north
}}
{{OHint
|location=Norwood
|lspan=3
|mile=5.93
|type=concur
|road={{jct|state=OH|SR|561|dir1=south|name1=Sherman Avenue}}
|notes=Western terminus of SR 561 concurrency
}}
{{OHint
|mile=6.25
|road={{jct|state=OH|SR|562|I|75|I|71|to2=yes}}
|notes=Exit 3 on SR 562 (Norwood Lateral Expressway); access via Norwood Avenue
}}
{{OHint
|mile=6.46
|type=concur
|road={{jct|state=OH|SR|561|dir1=north|name1=Ross Avenue}}
|notes=Eastern terminus of SR 561 concurrency
}}
{{OHint
|location=Kenwood
|mile=11.41
|road={{jct|state=OH|I|71|city1=Columbus|city2=Cincinnati}}
|notes=Exit 12 on I-71
}}
{{OHint
|location=Montgomery
|lspan=3
|mile=13.30
|type=concur
|road={{jct|state=OH|SR|126|dir1=west|name1=[[Ronald Reagan Cross County Highway|Ronald Reagan Highway]]}}
|notes=Roundabout; western terminus of SR 126 concurrency
}}
{{OHint
|mile=13.70
|type=concur
|road={{jct|state=OH|SR|126|dir1=east|name1=Remington Road}}
|notes=Eastern terminus of SR 126 concurrency
}}
{{OHint
|mile=16.15
|road={{jct|state=OH|I|275|I|71|SR|32|to2=yes|location1=[[Kentucky]]}}
|notes=Exit 50 on I-275
}}
<!--countyline=19.267-->
{{OHint
|county=Warren
|cspan=4
|location=Hopkinsville
|mile=24.64<!--5.37-->
|road={{jct|state=OH|SR|48|city1=South Lebanon|city2=Maineville}}
}}
{{OHint
|location=Morrow
|mile=29.97<!--10.70-->
|type=concur
|road={{jct|state=OH|SR|123|dir1=north|city1=Lebanon}}
|notes=Western terminus of SR 123 concurrency
}}
{{OHint
|township=Salem
|ctdab=Warren
|mile=31.70<!--12.43-->
|type=concur
|road={{jct|state=OH|SR|123|dir1=south|city1=Blanchester}}
|notes=Eastern terminus of SR 123 concurrency
}}
{{OHint
|township=Washington
|ctdab=Warren
|mile=37.54<!--18.27-->
|road={{jct|state=OH|SR|350|location1=[[Fort Ancient (Lebanon, Ohio)|Fort Ancient]]}}
}}
<!--countyline=39.037-->
{{OHint
|county=Clinton
|cspan=5
|township=Adams
|ctdab=Clinton
|mile=41.66<!--2.623-->
|road={{jct|state=OH|SR|380|dir1=north|city1=Xenia}}
|notes=Southern terminus of SR 380
}}
{{OHint
|location=Wilmington
|mile=48.00<!--8.961-->
|road={{jct|state=OH|US|68|SR|134|name2=South Street}}
}}
{{OHint
|township=Union
|ctdab=Clinton
|mile=51.10<!--12.067-->
|road={{jct|state=OH|SR|73|city1=Hillsboro|city2=Waynesville|I|71|dir2=south|to2=yes}}
|notes=Interchange
}}
{{OHint
|location=Reesville
|mile=56.75<!--17.714-->
|road={{jct|state=OH|SR|72|city1=Highland|city2=Jamestown}}
}}

{{OHint
|location=Sabina
|mile=58.89<!--19.848-->
|road={{jct|state=OH|SR|729|name1=Howard Street}}
}}
<!--countyline=61.956-->
{{OHint
|county=Fayette
|cspan=5
|location=Washington Court House
|lspan=5
|mile=68.52<!--6.567-->
|road={{jct|state=OH|US|35|I|71|to2=yes|city1=Dayton|city2=Chillicothe|location3=Fairgrounds}}
|notes=Exit 82 on US 35; access via [[collector-distributor roads]]
}}
{{OHint
|mile=69.69<!--7.733-->
|type=concur
|road={{jct|state=OH|US|62|dir1=west|SR|41|dir2=south|name1=Leesburg Avenue|name2=Highland Avenue}}
|notes=Western terminus of US 62 / SR 41 concurrency
}}
{{OHint
|mile=70.08<!--8.126-->
|type=concur
|road={{jct|state=OH|SR|41|dir1=north|name1=North Street}}
|notes=Eastern terminus of SR 41 concurrency
}}
{{OHint
|mile=70.32<!--8.364-->
|type=concur
|road={{jct|state=OH|US|62|SR|3|dir1=west|dir2=north|name2=Columbus Avenue}}
|notes=Eastern terminus of US 62 / SR 3 concurrency
}}
{{OHint
|mile=72.39<!--10.436-->
|road={{jct|state=OH|SR|753|US-Byp|35|to2=yes}}
}}
<!--countyline=79.572-->
{{OHint
|county=Pickaway
|cspan=7
|location=Atlanta
|mile=83.10<!--3.530-->
|road={{jct|state=OH|SR|207|city1=Mount Sterling|location2=[[Deer Creek State Park (Ohio)|Deer Creek]]|city3=Chillicothe}}
}}
{{OHint
|township=Wayne
|ctdab=Pickaway
|lspan=3
|mile=92.40<!--12.830-->
|road={{jct|state=OH|SR|138|dir1=west|city1=Clarksburg}}
|notes=Eastern terminus of SR 138
}}
{{OHint
|mile=94.20<!--14.630-->
|road={{jct|state=OH|SR|104|city1=Columbus|city2=Chillicothe}}
}}
{{OHint
|mile=95.62<!--16.050-->
|type=concur
|road={{jct|state=OH|SR|56|dir1=west|city1=Mount London|city2=London}}
|notes=Western terminus of SR 56 concurrency
}}
{{OHint
|location=Circleville
|lspan=3
|mile=96.79<!--17.220-->
|road={{jct|state=OH|US|23|city1=Columbus|city2=Chillicothe}}
|notes=Interchange
}}
{{OHint
|mile=97.18<!--17.610-->
|road={{jct|state=OH|SR|188|dir1=east|name1=Court Street}}
|notes=Western terminus of SR 188
}}
{{OHint
|mile=97.83<!--18.260-->
|type=concur
|road={{jct|state=OH|SR|56|dir1=east|name1=Main Street}}
|notes=Eastern terminus of SR 56 concurrency
}}
{{OHint
|county1=Pickaway
|county2=Fairfield
|township1=Washington
|ctdab1=Pickaway
|township2=Clearcreek
|ctdab2=Fairfield
|mile=103.53<!--23.960-->
|road={{jct|state=OH|SR|674|dir1=north}}
|notes=Southern terminus of SR 674
}}
{{OHint
|county=Fairfield
|cspan=8
|township=Hocking
|ctdab=Fairfield
|lspan=2
|mile=113.09<!--9.560-->
|road={{jct|state=OH|SR|159|dir1=south|city1=Tarlton}}
|notes=Northern terminus of SR 159
}}
{{OHint
|mile=114.16<!--10.630-->
|road={{jct|state=OH|US|33|city1=Logan|city2=Columbus}}
|notes=Interchange
}}
{{OHint
|location=Lancaster
|lspan=5
|mile=117.14<!--13.610-->
|type=concur
|road={{jct|state=OH|SR|188|dir1=west|name1=Cedar Hill Road}}
|notes=Western terminus of SR 188 concurrency
}}
{{OHint
|mile=117.64<!--14.110-->
|road={{jct|state=OH|SR|158|dir1=north|name1=Columbus Street}}
|notes=Southern terminus of SR 158
}}
{{OHint
|mile=117.93<!--14.400-->
|type=concur 
|road={{jct|state=OH|SR|37|dir1=west|name1=High Street}}
|notes=Western terminus of SR 37 concurrency
}}
{{OHint
|mile=118.77<!--15.240-->
|type=concur 
|road={{jct|state=OH|SR|188|dir1=east|name1=Cherry Street}}
|notes=Eastern terminus of SR 188 concurrency
}}
{{OHint
|mile=121.58<!--18.050-->
|type=concur 
|road={{jct|state=OH|SR|37|dir1=east|city1=Bremen|city2=Junction City|city3=New Lexington}}
|notes=Eastern terminus of SR 37 concurrency
}}
{{OHint
|location=Rushville
|mile=127.92<!--24.390-->
|road={{jct|state=OH|SR|664|SR|256|to2=yes|city1=Bremen}}
}}
<!--countyline=129.602-->
{{OHint
|county=Perry
|cspan=4
|location=Somerset
|lspan=3
|mile=135.61<!--6.010-->
|type=concur
|road={{jct|state=OH|SR|668|dir1=south}}
|notes=Western terminus of SR 668 concurrency
}}
{{OHint
|mile=135.78<!--6.180-->
|road={{jct|state=OH|SR|13|name1=Columbus Street}}
|notes=[[Traffic circle]]
}}
{{OHint
|mile=136.37<!--6.770-->
|type=concur
|road={{jct|state=OH|SR|668|dir1=north|city1=Brownsville|location2=[[Flint Ridge State Memorial|Flint Ridge]]}}
|notes=Eastern terminus of SR 668 concurrency
}}
{{OHint
|township=Madison
|ctdab=Perry
|mile=141.70<!--12.100-->
|road={{jct|state=OH|SR|204|dir1=west|city1=Millersport}}
|notes=Eastern terminus of SR 240
}}
<!--countyline=143.872-->
{{OHint
|county=Muskingum
|cspan=9
|location=East Fultonham
|mile=146.35<!--2.480-->
|road={{jct|state=OH|SR|345|dir1=south|city1=East Fultonham|city2=New Lexington|location3=[[Perry State Forest]]}}
|notes=Northern terminus of SR 345
}}
{{OHint
|township=Newton
|ctdab=Muskingum
|mile=150.30<!--6.424-->
|type=concur
|road={{jct|state=OH|SR|93|dir1=south|city1=Roseville|city2=Crooksville}}
|notes=Western terminus of SR 93 concurrency
}}
{{OHint
|location=South Zanesville
|mile=153.62<!--9.750-->
|road={{jct|state=OH|SR|719|dir1=east|SR|60|SR|146|SR|555|to2=yes}}
|notes=Western terminus of SR 719
}}
{{OHint
|location=Zanesville
|lspan=3
|mile=155.87<!--11.995-->
|type=concur
|road={{jct|state=OH|US|40|dir1=west|name1=Main Street}}
|notes=Western terminus of US 40 concurrency
}}
{{OHint
|mile=155.93<!--12.060-->
|type=concur
|road={{jct|state=OH|SR|60|dir1=south|SR|146|dir2=east|name2=9th Street|I|70|to3=yes}}
|notes=Western terminus of SR 60 / SR 146 concurrency
}}
{{OHint
|mile=156.05<!--12.178-->
|type=concur
|road={{jct|state=OH|SR|60|dir1=north|SR|146|dir2=west|name2=Underwood Street}}
|notes=Eastern terminus of SR 60 / SR 146 concurrency
}}
{{OHint
|location=Pleasant Grove
|mile=158.43<!--14.560-->
|type=concur
|road={{jct|state=OH|SR|93|dir1=north}}
|notes=Eastern terminus of SR 93 concurrency
}}
{{OHint
|township=Perry
|ctdab=Muskingum
|mile=165.54<!--21.670-->
|road={{jct|state=OH|I|70|location1=[[Wheeling, West Virginia|Wheeling]]|city2=Columbus}}
|notes=Exit 164 on I-70
}}
{{OHint
|location=New Concord
|mile=170.74<!--26.872-->
|road={{jct|state=OH|SR|83|I|70|to2=yes}}
}}
<!--countyline=171.606-->
{{OHint
|county=Guernsey
|cspan=9
|location=Cambridge
|lspan=4
|mile=177.18<!--5.576-->
|road={{jct|state=OH|SR|723|dir1=south|I|70|to2=yes}}
|notes=Northern terminus of SR 723
}}
{{OHint
|mile=179.23<!--7.626-->
|type=concur
|road={{jct|state=OH|SR|209|dir1=west|name1=5th Street}}
|notes=Western terminus of SR 209 concurrency
}}
{{OHint
|mile=179.51<!--7.901-->
|type=concur
|road={{jct|state=OH|SR|209|dir1=east|name1=Southgate Parkway|I|70|to2=yes}}
|notes=Eastern terminus of SR 209 concurrency
}}
{{OHint
|mile=179.84<!--8.234-->
|type=concur
|road={{jct|state=OH|US|40|dir1=east|name1=Wheeling Avenue}}
|notes=Eastern terminus of US 40 concurrency
}}
{{OHint
|township=Cambridge
|ctdab=Guernsey
|mile=181.98<!--10.372-->
|road={{jct|state=OH|I|77|city1=Marietta|city2=Cleveland}}
|notes=Exit 47 on I-77
}}
{{OHint
|township=Jefferson
|ctdab=Guernsey
|mile=188.31<!--16.708-->
|road=[[Salt Fork State Park]]
}}
{{OHint
|township=Madison
|ctdab=Guernsey
|mile=191.11<!--19.500-->
|road={{jct|state=OH|SR|285|name1=Jefferson Road}}
}}
{{OHint
|location=Antrim
|mile=194.96<!--23.356-->
|road={{jct|state=OH|SR|513|dir1=south|I|70|to2=yes}}
|notes=Northern terminus of SR 513
}}
{{OHint
|township=Londonderry
|ctdab=Guernsey
|mile=202.55<!--30.939-->
|type=concur
|road={{jct|state=OH|SR|800|dir1=south|city1=Barnesville}}
|notes=Western terminus of SR 800 concurrency
}}
<!--countyline=202.649-->
{{OHint
|county=Harrison
|cspan=8
|township=Freeport
|ctdab=Harrison
|mile=203.16<!--0.510-->
|type=concur
|road={{jct|state=OH|SR|800|dir1=north|city1=Freeport|location2=[[Clendening Dam]]}}
|notes=Eastern terminus of SR 800 concurrency
}}
{{OHint
|location=Piedmont
|mile=206.02<!--3.370-->
|road={{jct|state=OH|SR|331|dir1=east|city1=Holloway}}
|notes=Western terminus of SR 331
}}
{{OHint
|township=Cadiz
|ctdab=Harrison
|mile=212.54<!--9.890-->
|road={{jct|state=OH|SR|519|dir1=east|city1=New Athens}}
|notes=Western terminus of SR 519
}}
{{OHint|exit
|location=Cadiz
|lspan=2
|mile=219.29<!--16.640-->
|type=concur
|exit=219
|road={{jct|state=OH|US|250|dir1=west|city1=New Philadelphia}}
|notes=Western terminus of US 250 concurrency
}}
{{OHint|exit
|mile=220.14<!--17.490-->
|type=concur
|exit=220
|road={{jct|state=OH|US|250|dir1=east|SR|9|city1=Scio|city2=Cadiz|city3=Bridgeport}}
|notes=Eastern terminus of US 250 concurrency
}}
{{OHint|exit
|township=Green
|ctdab=Harrison
|mile=224.53<!--21.880-->
|type=concur
|exit=224
|road={{jct|state=OH|SR|151|dir1=west|city1=Jewett|city2=Scio}}
|notes=Western terminus of SR 151 concurrency
}}
{{OHint|exit
|location=Hopedale
|mile=226.27<!--23.620-->
|type=concur
|exit=226
|road={{jct|state=OH|SR|151|dir1=east|city1=Hopedale|city2=Smithfield}}
|notes=Eastern terminus of SR 151 concurrency
}}
{{OHint|exit
|township=Green
|ctdab=Harrison
|mile=227.87<!--25.220-->
|exit=-
|road=Township Road 65
|notes=Western terminus of freeway section
}}
<!--countyline=227.879-->
{{OHint|exit
|county=Jefferson
|cspan=9
|location=Bloomingdale
|mile=231.37<!--3.490-->
|exit=231
|road={{jct|state=OH|SR|152|city1=Bloomingdale|city2=Richmond|location2=Fairgrounds}}
}}
{{OHint|exit
|township=Wayne
|ctdab=Jefferson
|mile=233.78<!--5.900-->
|exit=233
|road=[[Reeds Mills, Ohio|Reeds Mills]], [[Broadacre, Ohio|Broadacre]]
|notes=Access via CR 22A
}}
{{OHint|exit
|location=Reeds Mill
|mile=235.21
|mile2=235.25
|exit=235
|type=incomplete
|road={{jct|state=OH|CR|22A|county1=Jefferson|city1=Wintersville|city2=Reeds Mills}}
|notes=Eastbound exit and westbound entrance
}}
{{OHint|exit
|location=Wintersville
|mile=237.48<!--9.600-->
|exit=237
|road={{jct|state=OH|SR|43|city1=Carrollton|city2=Wintersville}}
}}
{{OHint|exit
|location=none
|mile=240.18<!--12.300-->
|exit=240
|road=Lovers Lane – [[Steubenville, Ohio|Steubenville]]
}}
{{OHint|exit
|location=none
|mile=241.81<!--13.930-->
|exit=241
|road=John Scott Highway – [[Steubenville, Ohio|Steubenville]]
|notes=Serves [[Eastern Gateway Community College]]
}}
{{OHint|exit
|location=Alikanna
|mile=242.90<!--15.020-->
|exit=242
|type=concur
|road={{jct|state=OH|SR|7|dir1=north|SR|213|dir2=north|city1=East Liverpool}}
|notes=Western terminus of SR 7 concurrency; southern terminus of SR 213 (not signed westbound)
}}
{{OHint|exit
|location=Steubenville
|lspan=2
|mile=243.81<!--15.930-->
|exit=244A
|type=concur
|road={{jct|state=OH|SR|7|dir1=south|location1=[[Steubenville, Ohio|Downtown]]}}
|notes=Eastern terminus of SR 7 concurrency; signed as exit 244 westbound
}}
{{OHint|exit
|mile=244.20<!--16.320-->
|exit=244B
|type=incomplete
|road=University Boulevard
|notes=Westbuond exit is via exit 244A; serves [[Franciscan University of Steubenville]]
}}
{{jctbridge|exit
|river=[[Ohio River]]
|river_wide=yes
|mile=244.32<!--16.440-->
|mile2=0.0
|line=7
|bridge=[[Veterans Memorial Bridge (Steubenville, Ohio)|Veterans Memorial Bridge]]
}}
{{WVint|exit
|sspan=7
|county=Brooke
|cspan=2
|location=none
|mile=0.6
|exit=1
|type=concur
|road={{jct|state=WV|WV|2|dir1=south|city1=Follansbee|city2=Wheeling}}
|notes=Western terminus of WV 2 concurrency
}}
{{WVint|exit
|location=none
|mile=1.2
|exit=2
|type=concur
|road={{jct|state=WV|WV|2|dir1=north|name1=Main Street|location1=[[Weirton, West Virginia|Downtown Weirton]]}}
|notes=Eastern terminus of WV 2 concurrency
}}
{{jctco
|state=WV
|county=Hancock
}}
{{WVint|exit
|county=Brooke
|cspan=2
|location=Weirton
|lspan=4
|mile=3.2
|exit=3
|road={{jct|state=WV|CR|507|CR|1|county1=Brooke|county2=Brooke|name1=Harmon Creek Road|name2=Cove Road}}
}}
{{WVint|exit
|mile=4.3
|exit=4
|road={{jct|state=WV|CR|13|county1=Brooke|name1=Three Springs Drive|city1=Weirton}}
|notes=No CR 13 signage eastbound; serves [[West Virginia Northern Community College]]
}}
{{WVint|exit
|county1=Brooke
|county2=Hancock
|mile=5.5
|exit=5
|road={{jct|state=WV|WV|105|name1=Colliers Way}}
}}
{{WVint|exit
|county=Hancock
|mile=6.0
|exit=—
|road={{jct|state=PA|US|22|dir1=east|city1=Pittsburgh}}
|notes=Continuation into [[Pennsylvania]]
}}
{{jctbtm|col=8|keys=concur,incomplete}}