Editing Trichinosis (section)

===Lifecycle===
[[File:Trichinella LifeCycle.gif|thumb|upright=1.4|Lifecycle of ''Trichinella spiralis'']]

The typical lifecycle for ''T. spiralis'' involves humans, pigs, and rodents. A pig becomes infected when it eats infectious cysts in raw meat, often porcine [[carrion]] or a [[rat]] ([[sylvatic cycle]]). A human becomes infected by consuming raw or undercooked infected pork (domestic cycle). In the stomach, the [[cyst]]s from infected undercooked meat are acted on by [[pepsin]] and [[hydrochloric acid]], which help release the larvae from the cysts into the [[stomach]].<ref name=five>{{cite journal |author1=Capo, V. |author2=Despommier, D. D. |date=1996 |title=Clinical Aspects of Infection with ''Trichinella spp.'' |journal=Clinical Microbiology Reviews |volume=9 |issue=1 |pages=47–54 |doi=10.1128/cmr.9.1.47|pmid=8665476 |pmc=172881 }}</ref> The larvae then migrate to the [[small intestine]], and burrow into the [[intestinal mucosa]], where they molt four times before becoming adults.<ref name=five/>

Thirty to 34 hours after the cysts were originally ingested, the adults mate, and within five days produce larvae.<ref name="five"/> Adult worms can only reproduce for a limited time because the [[immune system]] eventually expels them from the small intestine.<ref name="five"/> The larvae then use their piercing mouthpart, called the "stylet", to pass through the [[Gastrointestinal wall|intestinal mucosa]] and enter the [[lymphatic vessel]]s, and then enter the [[Circulatory system|bloodstream]].<ref name="four"/>

The larvae travel by [[Capillary|capillaries]] to various organs, such as the [[retina]], [[Cardiac muscle|myocardium]], or [[lymph node]]s; however, only larvae that migrate to [[skeletal muscle]] cells survive and [[Microbial cyst|encyst]].<ref name="two"/> The larval host cell becomes a [[nurse cell]], in which the larva will be encapsulated, potentially for the life of the host, waiting for the host to be eaten. The development of a capillary network around the nurse cell completes encystation of the larva. Trichinosis is not soil-transmitted, as the [[Parasitism|parasite]] does not lay eggs, nor can it survive long outside a host.<ref name=Mason2014/><ref>{{cite journal |title=Epidemiology, diagnosis, treatment, and control of trichinellosis |journal=Clinical Microbiology Reviews |date=January 2009 |pmc=2620635 |pmid=19136437 |pages=127–45, Table of Contents|volume=22 |issue=1 |doi=10.1128/CMR.00026-08 |first1=Bruno |last1=Gottstein |first2=Edoardo |last2=Pozio |first3=Karsten |last3=Nöckler}}</ref>