Editing Thiamine (section)

==Medical uses==
{{See also|Prenatal vitamins}}
During pregnancy, thiamine is sent to the [[fetus]] via the [[placenta]]. Pregnant women have a greater requirement for the vitamin than other adults, especially during the [[Pregnancy#Third trimester|third trimester]].<ref name=ods/><ref name=lpi/> Pregnant women with [[hyperemesis gravidarum]] are at an increased risk of thiamine deficiency due to losses when vomiting.<ref>{{cite journal | vauthors = Oudman E, Wijnia JW, Oey M, van Dam M, Painter RC, Postma A | title = Wernicke's encephalopathy in hyperemesis gravidarum: A systematic review | journal = European Journal of Obstetrics, Gynecology, and Reproductive Biology | volume = 236 | pages = 84–93 | date = May 2019 | pmid = 30889425 | doi = 10.1016/j.ejogrb.2019.03.006 | hdl = 1874/379566 | s2cid = 84184482| hdl-access = free }}</ref> In [[Lactation|lactating]] women, thiamine is delivered in breast milk even if it results in thiamine deficiency in the mother.<ref name="DRItext" /><ref name=":0">{{cite journal | vauthors = Butterworth RF | date = December 2001 |title=Maternal thiamine deficiency: still a problem in some world communities | journal = The American Journal of Clinical Nutrition | volume = 74 |issue=6 | pages = 712–3 | doi = 10.1093/ajcn/74.6.712 | pmid = 11722950 | doi-access = free }}</ref>

Thiamine is important not only for [[Mitochondrion|mitochondrial membrane]] development, but also for [[Synaptosome|synaptic membrane]] function.<ref>{{cite journal | vauthors = Kloss O, Eskin NA, Suh M | title = Thiamin deficiency on fetal brain development with and without prenatal alcohol exposure | journal = Biochemistry and Cell Biology | volume = 96 | issue = 2 | pages = 169–77 | date = April 2018 | pmid = 28915355 | doi = 10.1139/bcb-2017-0082 | hdl = 1807/87775 | hdl-access = free }}</ref> It has also been suggested that a deficiency hinders brain development in infants and may be a cause of [[sudden infant death syndrome]].<ref name="Lons2006">{{cite journal | vauthors = Lonsdale D | title = A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives | journal = Evidence-Based Complementary and Alternative Medicine | volume = 3 | issue = 1 | pages = 49–59 | date = March 2006 | pmid = 16550223 | pmc = 1375232 | doi = 10.1093/ecam/nek009 }}</ref>