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===Antidepressants=== {{Main|Antidepressant}} Antidepressants are drugs used to treat [[clinical depression]], and they are also often used for anxiety and other disorders. Most antidepressants will hinder the breakdown of [[serotonin]], [[norepinephrine]], and/or [[dopamine]]. A commonly used class of antidepressants are called [[selective serotonin reuptake inhibitor]]s (SSRIs), which act on serotonin transporters in the brain to increase levels of serotonin in the [[synaptic cleft]].<ref name="Stahl"/> Another is the [[serotonin-norepinephrine reuptake inhibitors]] (SNRIs), which increase both serotonin and norepinephrine. Antidepressants will often take 3β5 weeks to have a noticeable effect as the regulation of receptors in the brain adapts. There are multiple classes of antidepressants which have different mechanisms of action. Another type of antidepressant is a [[monoamine oxidase inhibitor]] (MAOI), which is thought to block the action of [[monoamine oxidase]], an enzyme that breaks down serotonin and [[norepinephrine]]. MAOIs are not used as first-line treatment due to the risk of [[hypertensive crisis]] related to the consumption of foods containing the amino acid [[tyramine]].<ref name="Stahl"/> Common antidepressants: *[[Fluoxetine]] (Prozac), SSRI *[[Paroxetine]] (Paxil, Seroxat), SSRI *[[Citalopram]] (Celexa), SSRI *[[Escitalopram]] (Lexapro), SSRI *[[Sertraline]] (Zoloft), SSRI *[[Duloxetine]] (Cymbalta), SNRI *[[Venlafaxine]] (Effexor), SNRI *[[Bupropion]] (Wellbutrin), [[Norepinephrine-dopamine reuptake inhibitor|NDRI]]<ref>{{cite journal| author =Stephen M. Stahl, M.D.| title =A Review of the Neuropharmacology of Bupropion, a Dual Norepinephrine and Dopamine Reuptake Inhibitor | publisher =Journal of Clinical Psychiatry; 6(04) 159-166 2004 PHYSICIANS POSTGRADUATE PRESS, INC| year = 2004 | url = http://www.psychiatrist.com/pcc/pccpdf/v06n04/v06n0403.pdf | access-date =2006-09-02 |display-authors=etal}}</ref> *[[Mirtazapine]] (Remeron), [[NaSSA]] *[[Isocarboxazid]] (Marplan), MAOI *[[Phenelzine]] (Nardil), MAOI *[[Tranylcypromine]] (Parnate), MAOI *[[Amitriptyline]] (Elavil), TCA
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