Editing Post-translational modification (section)

===Non-enzymatic modifications ''in vivo''===
Examples of non-enzymatic PTMs are glycation, glycoxidation, nitrosylation, oxidation, succination, and lipoxidation.<ref>"The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity" PMID 33203089 PMC7696601</ref>
* [[glycation]], the addition of a sugar molecule to a protein without the controlling action of an enzyme.
* [[carbamylation]] the addition of [[Isocyanic acid]] to a protein's N-terminus or the side-chain of Lys.<ref name="pmid21768218">{{cite journal | vauthors = Jaisson S, Pietrement C, Gillery P | title = Carbamylation-derived products: bioactive compounds and potential biomarkers in chronic renal failure and atherosclerosis | journal = Clinical Chemistry | volume = 57 | issue = 11 | pages = 1499–505 | date = November 2011 | pmid = 21768218 | doi = 10.1373/clinchem.2011.163188 | doi-access = free }}</ref>
* [[carbonylation]] the addition of carbon monoxide to other organic/inorganic compounds.
* spontaneous [[isopeptide bond]] formation, as found in many surface proteins of [[Gram-positive bacteria]].<ref name="pmid21055949">{{cite journal | vauthors = Kang HJ, Baker EN | title = Intramolecular isopeptide bonds: protein crosslinks built for stress? | journal = Trends in Biochemical Sciences | volume = 36 | issue = 4 | pages = 229–37 | date = April 2011 | pmid = 21055949 | doi = 10.1016/j.tibs.2010.09.007 }}</ref>