Editing Phospholipid (section)

== Applications ==
Phospholipids have been widely used to prepare liposomal, ethosomal and other nanoformulations of topical, oral and [[Route of administration#Parenteral|parenteral]] drugs for differing reasons like improved bio-availability, reduced toxicity and increased permeability across membranes. Liposomes<ref>{{Cite journal |last1=Akbarzadeh |first1=Abolfazl |last2=Rezaei-Sadabady |first2=Rogaie |last3=Davaran |first3=Soodabeh |last4=Joo |first4=Sang Woo |last5=Zarghami |first5=Nosratollah |last6=Hanifehpour |first6=Younes |last7=Samiei |first7=Mohammad |last8=Kouhi |first8=Mohammad |last9=Nejati-Koshki |first9=Kazem |date=2013-02-22 |title=Liposome: classification, preparation, and applications |journal=Nanoscale Research Letters |volume=8 |issue=1 |pages=102 |doi=10.1186/1556-276X-8-102 |doi-access=free |issn=1931-7573 |pmc=3599573 |pmid=23432972|bibcode=2013NRL.....8..102A }}</ref> are often composed of [[phosphatidylcholine]]-enriched phospholipids and may also contain mixed phospholipid chains with [[surfactant]] properties. The ethosomal formulation of [[ketoconazole]] using phospholipids is a promising option for transdermal delivery in fungal infections.<ref>[http://ethesis.nitrkl.ac.in/5377/1/411LS2068.pdf Ketoconazole Encapsulated Liposome and Ethosome: GUNJAN TIWARI].</ref> Advances in phospholipid research lead to exploring these biomolecules and their conformations using lipidomics<ref>{{Cite journal |last1=Yang |first1=Kui |last2=Han |first2=Xianlin |date=November 2016 |title=Lipidomics: Techniques, applications, and outcomes related to biomedical sciences |journal=Trends in Biochemical Sciences |volume=41 |issue=11 |pages=954–969 |doi=10.1016/j.tibs.2016.08.010 |issn=0968-0004 |pmc=5085849 |pmid=27663237}}</ref>.{{citation needed|date=September 2022}}