Editing Peroxisome (section)

== Genes ==
PEX genes encode the protein machinery (peroxins) required for proper peroxisome assembly. Peroxisomal membrane proteins are imported through at least two routes, one of which depends on the interaction between peroxin 19 and peroxin 3, while the other is required for the import of peroxin 3, either of which may occur without the import of matrix (lumen) enzymes, which possess the peroxisomal targeting signal PTS1 or PTS2 as previously discussed.<ref>{{cite journal|vauthors=Fang Y, Morrell JC, Jones JM, Gould SJ|title=PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins|journal=Journal of Cell Biology|volume=164|issue=6|pages=863–875|doi=10.1083/jcb.200311131|year=2004|pmid=15007061|pmc=2172291|doi-access=free}}</ref>  Elongation of the peroxisome membrane and the final fission of the organelle are regulated by Pex11p.<ref>{{cite journal|vauthors=Williams C, Opalinski L, Landgraf C, Costello J, Schrader M, Krikken AM, Knoops K, Kram AM, Volkmer R, van der Klei IJ|title=The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=112|issue=20|pages=6377–6382|year=2015|pmid=25941407|pmc=4443378|doi=10.1073/pnas.1418736112|doi-access=free|bibcode=2015PNAS..112.6377W }}</ref>

Genes that encode peroxin proteins include: [[PEX1]], [[PEX2]] (PXMP3), [[PEX3]], [[PEX5]], [[PEX6]], [[PEX7]], PEX9,<ref>{{cite journal | vauthors = Effelsberg D, Cruz-Zaragoza LD, Schliebs W, Erdmann R | title = Pex9p is a new yeast peroxisomal import receptor for PTS1-containing proteins | journal = Journal of Cell Science | volume = 129 | issue = 21 | pages = 4057–4066 | date = November 2016 | pmid = 27678487 | doi = 10.1242/jcs.195271 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Yifrach E, Chuartzman SG, Dahan N, Maskit S, Zada L, Weill U, Yofe I, Olender T, Schuldiner M, Zalckvar E | display-authors = 6 | title = Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor | journal = Journal of Cell Science | volume = 129 | issue = 21 | pages = 4067–4075 | date = November 2016 | pmid = 27663510 | pmc = 6275125 | doi = 10.1242/jcs.195255 }}</ref> [[PEX10]], [[PEX11A]], [[PEX11B]], [[PEX11G]], [[PEX12]], [[PEX13]], [[PEX14]], [[PEX16]], [[PEX19]], [[PEX26]], [[PEX28]], [[PEX30]], and [[PEX31]]. Between organisms, PEX numbering and function can differ.