Editing Microvillus (section)

===Destruction===
The destruction of microvilli can occur in certain diseases because of the rearrangement of cytoskeleton in host cell. 
This is seen in infections caused by EPEC subgroup ''[[Escherichia coli]]'', in [[Coeliac disease|celiac]] disease, and microvillus inclusion disease<ref>Malathy Kapali, MD, Ronald Jaffe, MD and Rocco M Agostini Jr. B.Sc. Final Diagnosis: Microvillus Inclusion Disease. {{cite web |url=http://path.upmc.edu/cases/case163/dx.html |title=Final Diagnosis -- Case 163 |access-date=2006-02-19 |url-status=dead |archive-url=https://web.archive.org/web/19991006051512/http://path.upmc.edu/cases/case163/dx.html |archive-date=1999-10-06 }}</ref> (an inherited disease characterized by defective microvilli and presence of cytoplasmic inclusions of the cell membrane other than the apical surface).

The destruction of microvilli can actually be beneficial sometimes, as in the case of elimination of microvilli on white blood cells which can be used to combat auto immune diseases.<ref>Shattuck, T. (2004) Cells studied for immune function. {{cite web |url=http://www.dartmouth.edu/~vox/0405/0927/cells.html |title=Cells studied for immune function |access-date=2006-02-19 |url-status=dead |archive-url=https://web.archive.org/web/20160820194017/http://www.dartmouth.edu/~vox/0405/0927/cells.html |archive-date=2016-08-20 }}.</ref>

Congenital lack of microvilli in the intestinal tract causes [[microvillus inclusion disease|microvillus atrophy]], a rare, usually fatal condition found in new-born babies.