Editing Goitre (section)

==Epidemiology==
[[File:Iodine deficiency world map - DALY - WHO2002.svg|thumb|upright=1.15|[[Disability-adjusted life year]] for iodine deficiency per 100,000&nbsp;inhabitants in 2002.<ref>{{cite web |url=https://www.who.int/entity/healthinfo/statistics/bodgbddeathdalyestimates.xls |title=Mortality and Burden of Disease Estimates for WHO Member States in 2002|format=xls |work=World Health Organization|year=2002 }}</ref>{{Div col|small=yes|colwidth=10em}}
{{legend|#b3b3b3|no data}}
{{legend|#ffff65|fewer than 50}}
{{legend|#fff200|50–100}}
{{legend|#ffdc00|100–150}}
{{legend|#ffc600|150–200}}
{{legend|#ffb000|200–250}}
{{legend|#ff9a00|250–300}}
{{legend|#ff8400|300–350}}
{{legend|#ff6e00|350–400}}
{{legend|#ff5800|400–450}}
{{legend|#ff4200|450–500}}
{{legend|#ff2c00|500–800}}
{{legend|#cb0000|more than 800}}
{{div col end}}]]
Goitre is more common among women, but this includes the many types of goitre caused by autoimmune problems, and not only those caused by simple lack of iodine.<ref>1</ref>

Iodine mainly accumulates in the sea and in the [[topsoil]]. Before iodine enrichment programs, goiters were common in areas with repeated flooding or glacial activities, which erodes the topsoil. It is endemic in populations where the intake of iodine is less than 10 μg per day.<ref>[https://web.archive.org/web/20210606021115/https://apps.who.int/iris/bitstream/handle/10665/133706/WHO_NMH_NHD_EPG_14.5_eng.pdf Goitre as a determinant of the prevalence and severity of iodine deficiency disorders in populations], World Health Organization - 2014</ref>

Examples of such regions include the alpine regions of Southern Europe (such as Switzerland), the Himalayans, the [[Great Lakes Basin|Great Lakes basin]], etc. As reported in 1923, all the domestic animals have goiter in some of the glacial valleys of Southern Alaska. It was so severe in [[Pemberton Meadows]] that it was difficult to raise young animals there.<ref>{{Cite journal |last=Kimball |first=O. P. |title=The Prevention of Simple Goiter |date=February 1923 |journal=American Journal of Public Health |volume=13 |issue=2 |pages=81–87 |doi=10.2105/ajph.13.2.81-a |pmid=18010882 |pmc=1354367 }}</ref>