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===Special precautions=== Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, in alcohol- or drug-dependent individuals, and in individuals with [[comorbid]] [[psychiatric disorders]].<ref>{{cite journal | vauthors = Authier N, Balayssac D, Sautereau M, Zangarelli A, Courty P, Somogyi AA, Vennat B, Llorca PM, Eschalier A | display-authors = 6 | title = Benzodiazepine dependence: focus on withdrawal syndrome | journal = Annales Pharmaceutiques Françaises | volume = 67 | issue = 6 | pages = 408–413 | date = November 2009 | pmid = 19900604 | doi = 10.1016/j.pharma.2009.07.001 }}</ref> Impairment of driving skills with a resultant increased risk of [[road traffic accidents]] is probably the most important adverse effect. This side-effect is not unique to flunitrazepam but also occurs with other hypnotic drugs. Flunitrazepam seems to have a particularly high risk of road traffic accidents compared to other hypnotic drugs. Extreme caution should be exercised by drivers after taking flunitrazepam.<ref>{{cite journal | vauthors = Gustavsen I, Bramness JG, Skurtveit S, Engeland A, Neutel I, Mørland J | title = Road traffic accident risk related to prescriptions of the hypnotics zopiclone, zolpidem, flunitrazepam and nitrazepam | journal = Sleep Medicine | volume = 9 | issue = 8 | pages = 818–822 | date = December 2008 | pmid = 18226959 | doi = 10.1016/j.sleep.2007.11.011 | hdl-access = free | hdl = 10852/34650 }}</ref><ref name=UKdrivingregs2014>UK Dept. of Transport. July 2014. {{cite web | url = https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/325275/healthcare-profs-drug-driving.pdf | title = Guidance for healthcare professionals on drug driving | work = The Department for Transport | date = 2014 | location = London }}</ref>
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