Editing Dementia praecox (section)

===Cause===
Though his work and that of his research associates had revealed a role for heredity, Kraepelin realized nothing could be said with certainty about the aetiology of dementia praecox, and he left out speculation regarding brain disease or neuropathology in his diagnostic descriptions. Nevertheless, from the 1896 edition onwards Kraepelin made clear his belief that poisoning of the brain, "auto-intoxication," probably by sex hormones, may underlie dementia praecox&nbsp;– a theory also entertained by Eugen Bleuler. Both theorists insisted dementia praecox is a biological disorder, not the product of psychological trauma. Thus, rather than a disease of hereditary degeneration or of structural brain pathology, Kraepelin believed dementia praecox was due to a systemic or "whole body" disease process, probably metabolic, which gradually affected many of the tissues and organs of the body before affecting the brain in a final, decisive cascade.<ref>{{cite web|last=Noll|first=Richard|title=Whole Body Madness|url=http://www.psychiatrictimes.com/display/article/10168/2104852|publisher=Psychiatric times|access-date=26 September 2012}}</ref> Kraepelin, recognizing dementia praecox in Chinese, Japanese, Tamil and Malay patients, suggested in the eighth edition of {{lang|de|Psychiatrie}} that, "we must therefore seek the real cause of dementia praecox in conditions which are spread all over the world, which thus do not lie in race or in climate, in food or in any other general circumstance of life..."{{sfn|Noll|2007a|p=[https://books.google.com/books?id=jzoJxps189IC&pg=PA127 127]}}