Editing Cytomegalovirus (section)

== History ==
''Cytomegalovirus'' was first observed by German pathologist [[Hugo Ribbert]] in 1881 when he noticed enlarged cells with enlarged nuclei present in the cells of an infant.<ref>{{Cite book | veditors = Reddehase MJ, Lemmermann N | pages = xxiv |chapter=Preface |title=Cytomegaloviruses: Molecular Biology and Immunology |publisher=Horizon Scientific Press |year=2006 |isbn=9781904455028 }}</ref> Years later, between 1956 and 1957, [[Thomas Huckle Weller]] together with Smith and Rowe independently isolated the virus, known thereafter as "cytomegalovirus".<ref>{{cite journal | vauthors = Craig JM, Macauley JC, Weller TH, Wirth P | title = Isolation of intranuclear inclusion producing agents from infants with illnesses resembling cytomegalic inclusion disease | journal = Proceedings of the Society for Experimental Biology and Medicine | volume = 94 | issue = 1 | pages = 4–12 | date = January 1957 | pmid = 13400856 | doi = 10.3181/00379727-94-22841 | s2cid = 29263626 }}</ref> In 1990, the first draft of human cytomegalovirus genome was published,<ref>{{cite book | vauthors = Chee MS, Bankier AT, Beck S, Bohni R, Brown CM, Cerny R, Horsnell T, Hutchison CA, Kouzarides T, Martignetti JA | chapter = Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169 | title = Cytomegaloviruses | display-authors = 6 | volume = 154 | pages = 125–69 | date = 1990 | pmid = 2161319 | doi = 10.1007/978-3-642-74980-3_6 | publisher = Springer Berlin Heidelberg | isbn = 978-3-642-74982-7 | series = Current Topics in Microbiology and Immunology }}</ref> the biggest contiguous genome sequenced at that time.<ref>{{cite journal | vauthors = Martí-Carreras J, Maes P | title = Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challenges | journal = Virus Genes | volume = 55 | issue = 2 | pages = 138–164 | date = April 2019 | pmid = 30604286 | pmc = 6458973 | doi = 10.1007/s11262-018-1627-3 }}</ref>