Editing Charcot–Marie–Tooth disease (section)

== Treatment and Management ==
[[File:Charcot Marie Tooth CMT.jpg|thumb|[[Orthotics#Ankle–foot orthoses (AFO) in the field of paralysis orthoses|Ankle-foot orthosis]]]]
There is no cure for CMT, but its symptoms can be managed to maintain quality of life. Physical and occupational therapy can help preserve muscle strength, flexibility, and mobility<ref>{{Cite web |title=Charcot-Marie-Tooth Disease {{!}} National Institute of Neurological Disorders and Stroke |url=https://www.ninds.nih.gov/health-information/disorders/charcot-marie-tooth-disease |access-date=2025-04-11 |website=www.ninds.nih.gov |language=en}}</ref>

Orthopedic devices like [[Orthotics|ankle-foot orthoses]] (AFOs) are commonly used to correct foot drop and improve gait. In some cases, surgical interventions may be necessary to straighten toes, lower arches, or fuse joints to enhance stability. Pain management may involve physical therapy, assistive devices, or medications for neuropathic pain. Patients are advised to avoid prolonged immobility, which can accelerate disease progression. Certain drugs, such as vincristine (a chemotherapy agent), should be avoided altogether in CMT patients due to their known toxicity to nerves. Regular follow-up with healthcare providers is essential to adapt care as the disease progresses.<ref>{{Cite journal |last1=Beloribi-Djefaflia |first1=S. |last2=Attarian |first2=S. |date=2023-01-01 |title=Treatment of Charcot-Marie-Tooth neuropathies |url=https://linkinghub.elsevier.com/retrieve/pii/S0035378722008451 |journal=Revue Neurologique |volume=179 |issue=1 |pages=35–48 |doi=10.1016/j.neurol.2022.11.006 |pmid=36588067 |issn=0035-3787}}</ref>