Editing Hepatitis (section)

=== Alcoholic hepatitis ===
[[Alcoholic hepatitis]] (AH) in its severe form has a one-month mortality as high as 50%.<ref name="Chayanupatkul & Liangpunsakul">{{Cite journal|last1=Chayanupatkul|first1=Maneerat|last2=Liangpunsakul|first2=Suthat|date=2014-05-28|title=Alcoholic hepatitis: a comprehensive review of pathogenesis and treatment|journal=World Journal of Gastroenterology|volume=20|issue=20|pages=6279–6286|doi=10.3748/wjg.v20.i20.6279|issn=2219-2840|pmc=4033465|pmid=24876748 |doi-access=free }}</ref><ref name="Definition, epidemiology, and magnitude" /><ref name="Singal Kamath Gores Shah">{{Cite journal|last1=Singal|first1=Ashwani K.|last2=Kamath|first2=Patrick S.|last3=Gores|first3=Gregory J.|last4=Shah|first4=Vijay H.|date=2014-04-01|title=Alcoholic hepatitis: current challenges and future directions|journal=Clinical Gastroenterology and Hepatology|volume=12|issue=4|pages=555–564; quiz e31–32|doi=10.1016/j.cgh.2013.06.013|issn=1542-7714|pmc=3883924|pmid=23811249}}</ref> Most people who develop AH are men but women are at higher risk of developing AH and its complications likely secondary to high body fat and differences in alcohol metabolism.<ref name="Definition, epidemiology, and magnitude" /> Other contributing factors include younger age <60, binge pattern drinking, poor nutritional status, obesity and hepatitis C co-infection.<ref name="Definition, epidemiology, and magnitude" /> It is estimated that as much as 20% of people with AH are also infected with hepatitis C.<ref name="Shoreibah, Bhupinderjit, Singal">{{Cite journal|last1=Shoreibah|first1=Mohamed|last2=Anand|first2=Bhupinderjit S.|last3=Singal|first3=Ashwani K.|date=2014-09-14|title=Alcoholic hepatitis and concomitant hepatitis C virus infection|journal=World Journal of Gastroenterology|volume=20|issue=34|pages=11929–11934|doi=10.3748/wjg.v20.i34.11929|issn=2219-2840|pmc=4161778|pmid=25232227 |doi-access=free }}</ref>  In this population, the presence of hepatitis C virus leads to more severe disease with faster progression to cirrhosis, hepatocellular carcinoma and increased mortality.<ref name="Definition, epidemiology, and magnitude" /><ref name="Shoreibah, Bhupinderjit, Singal" /><ref>{{Cite journal|last1=Singal|first1=Ashwani K.|last2=Anand|first2=Bhupinder S.|date=2007-09-01|title=Mechanisms of synergy between alcohol and hepatitis C virus|journal=Journal of Clinical Gastroenterology|volume=41|issue=8|pages=761–772|doi=10.1097/MCG.0b013e3180381584|issn=0192-0790|pmid=17700425|s2cid=19482895}}</ref> Obesity increases the likelihood of progression to cirrhosis in cases of alcoholic hepatitis.<ref name="Definition, epidemiology, and magnitude" />  It is estimated that 70% of people who have AH will progress to cirrhosis.<ref name="Definition, epidemiology, and magnitude" />