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====Prostate cancer==== A 2016 review concluded that "current evidence from [[observational study|observational studies]] and small clinical trials is not robust enough to understand whether soy protein or [[isoflavone]] supplements may help prevent or inhibit the progression of [[prostate cancer]]."<ref name=lpi/> A 2010 review showed that neither soy foods nor isoflavone supplements alter measures of bioavailable [[testosterone]] or [[estrogen]] concentrations in men.<ref>{{cite journal |pages=997β1007 |doi=10.1016/j.fertnstert.2009.04.038 |title=Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: Results of a meta-analysis |year=2010 |last1=Hamilton-Reeves |first1=Jill M. |last2=Vazquez |first2=Gabriela |last3=Duval |first3=Sue J. |last4=Phipps |first4=William R. |last5=Kurzer |first5=Mindy S. |last6=Messina |first6=Mark J. |journal=[[Fertility and Sterility]]|volume=94 |issue=3 |pmid=19524224}}</ref> Soy consumption has been shown to have no effect on the levels and quality of [[sperm]].<ref>{{cite journal |pages=2095β2104 |doi=10.1016/j.fertnstert.2010.03.002 |title=Soybean isoflavone exposure does not have feminizing effects on men: A critical examination of the clinical evidence |year=2010 |last1=Messina |first1=Mark |journal=[[Fertility and Sterility]]|volume=93 |issue=7 |pmid=20378106|doi-access=free }}</ref> [[Meta-analysis|Meta-analyses]] on the association between soy consumption and prostate cancer risk in men concluded that dietary soy may lower the risk of prostate cancer.<ref>{{cite journal |first1=Lin |last1=Yan |first2=Edward L |last2=Spitznagel |title=Soy consumption and prostate cancer risk in men: a revisit of a meta-analysis |journal=The American Journal of Clinical Nutrition|pmid=19211820 |doi=10.3945/ajcn.2008.27029 |year=2009 |volume=89 |issue=4 |pages=1155β63|doi-access=free }}</ref><ref name="vandie">{{cite journal | last1=van Die | first1=MD | last2=Bone | first2=KM | last3=Williams | first3=SG | last4=Pirotta | first4=MV | title=Soy and soy isoflavones in prostate cancer: a systematic review and meta-analysis of randomized controlled trials. | journal=[[BJU International]]| volume=113 | issue=5b | year=2014 | pmid=24053483 | doi=10.1111/bju.12435 | pages=E119β30| s2cid=39315041 }}</ref>
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