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=== Bipolar disorder === One of the main behavioral symptoms of [[bipolar disorder]] is abnormal sleep. Studies have suggested that 23-78% of individuals with bipolar disorders consistently report symptoms of excessive time spent sleeping, or hypersomnia.<ref name=":19" /> The pathogenesis of bipolar disorder, including the higher risk of suicidal ideation, could possibly be linked to circadian rhythm variability, and sleep disturbances are a good predictor of mood swings.<ref name=":20">{{cite journal | vauthors = Steardo L, de Filippis R, Carbone EA, Segura-Garcia C, Verkhratsky A, De Fazio P | title = Sleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms | journal = Frontiers in Psychiatry | volume = 10 | pages = 501 | date = 2019-07-18 | pmid = 31379620 | pmc = 6656854 | doi = 10.3389/fpsyt.2019.00501 | doi-access = free | author-link5 = Alexei Verkhratsky }}</ref> The most common sleep-related symptom of bipolar disorder is insomnia, in addition to hypersomnia, nightmares, poor sleep quality, OSA, extreme daytime sleepiness, etc.<ref name=":20" /> Moreover, animal models have shown that sleep debt can induce episodes of bipolar mania in laboratory mice, but these models are still limited in their potential to explain bipolar disease in humans with all its multifaceted symptoms, including those related to sleep disturbances.<ref>{{cite journal | vauthors = Logan RW, McClung CA | title = Animal models of bipolar mania: The past, present and future | journal = Neuroscience | volume = 321 | pages = 163β188 | date = May 2016 | pmid = 26314632 | pmc = 4766066 | doi = 10.1016/j.neuroscience.2015.08.041 }}</ref>
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